Objective: To evaluate the viability of Saccharomyces boulardii after PO administration in clinically normal horses and its efficacy as a treatment for horses with acute enterocolitis.
Design: Prospective study.
Animals: 5 clinically normal horses and 14 horses with acute enterocolitis.
Procedure: Feces were collected from 5 clinically normal horses and submitted for microbial culture for 2 days prior to administration of a lyophilized form of S. boulardii (25 or 50 g, PO, q 12 h) for 10 days. Feces were collected for microbial culture 5 and 10 days after treament initiation and 10 days after treatment was discontinued. Fourteen horses with acute enterocolitis were randomly allocated to receive a placebo or S. boulardii (25 g), PO, every 12 hours for 14 days.
Results: S. boulardii was not detected in feces of clinically normal horses. After administration, yeast survived within the gastroinestinal tract but did not permanently colonize it. In horses with acute enterocolitis, the severity and duration of gastrointestinal tract disease during hospitalization were significantly decreased in horses receiving S. boulardii, compared with horses receiving the placebo.
Conclusions And Clinical Relevance: Administration of S. boulardii may help decrease the severity and duration of clinical signs in horses with acute enterocolitis.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.2460/javma.2005.227.954 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Biochemical Mechanisms and Rehabilitation Strategies in Osteoporosis-Related Pain: A Systematic Review.
Clin Pract
December 2024
Department of Experimental Medicine (Di.Me.S), University of Salento, 73100 Lecce, Italy.
Background/objectives: Osteoporosis causes a bone mass reduction and often determines acute and chronic pain. Understanding the biochemical and neurophysiological mechanisms behind this pain is crucial for developing new, effective rehabilitative and therapeutic approaches. This systematic review synthesizes recent advances in muscle-bone interactions and molecular pathways related to osteoporosis-associated pain.
View Article and Find Full Text PDFSmart medical report: efficient detection of common and rare diseases on common blood tests.
Front Digit Health
December 2024
Aesculab Medical Solutions, Black Horse Group Ltd., Debrecen, Hungary.
Introduction: The integration of AI into healthcare is widely anticipated to revolutionize medical diagnostics, enabling earlier, more accurate disease detection and personalized care.
Methods: In this study, we developed and validated an AI-assisted diagnostic support tool using only routinely ordered and broadly available blood tests to predict the presence of major chronic and acute diseases as well as rare disorders.
Results: Our model was tested on both retrospective and prospective datasets comprising over one million patients.
Case report: Incomplete bypass ileocolostomy without partial typhlectomy in five horses with acute, non-reducible cecocolic intussusceptions and review of literature.
Front Vet Sci
November 2024
Department for Horses, Faculty of Veterinary Medicine, University of Leipzig, Leipzig, Germany.
Cecocolic intussusceptions are a rare condition of acute colic in horses requiring immediate surgical intervention due to persistent uncontrollable pain and ongoing ischemic cecal necrosis. Particularly in cases where reduction of the intussusception is surgically not feasible surgical interventions such as partial typhlectomy through colotomy (partial cecal amputation) combined with or without cecal bypass techniques are described. Alternatively, surgical interventions can also be performed without partial typhlectomy via incomplete bypass ileocolostomy.
View Article and Find Full Text PDFExploring the combined toxicity of boron nitride nanosheets, cadmium and natural organic matter on Daphnia magna.
Aquat Toxicol
December 2024
Brazilian Nanotechnology National Laboratory (LNNano), Brazilian Center for Research in Energy and Materials (CNPEM), Campinas, Sao Paulo, Brazil. Electronic address:
The increase in anthropogenic activities has led to the release of numerous chemicals and pollutants into aquatic ecosystems, raising significant concerns for water quality and health. Among the emerging issues is the interaction between pollutants and nanomaterials (mixture effects). In this work, it was studied the combined toxicity of boron nitride nanosheets (BNNS) and cadmium (Cd) incorporating the influence of natural organic matter (NOM) to enhance ecological relevance for the first time.
View Article and Find Full Text PDFIce application without water drainage supports optimal hoof cooling in adult horses.
J Equine Vet Sci
December 2024
Virginia Tech, School of Animal Sciences, 175 West Campus Dr, Blacksburg, VA 24061 USA.
Cryotherapy is often used to reduce inflammation in acute equine laminitis cases. Certain hoof temperatures have been suggested as effective in minimizing the inflammatory process; however, there is limited evidence on which methods are best at achieving these temperatures. Our objective was to determine how different methods of cryotherapy influence the rate and extent of cooling for the equine hoof wall.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!