Novel amphoteric particles are prepared by an interfacial polyaddition reaction of ethylene glycol diglycidyl ether (EGDGE) and L-lysine in a water-in-oil (W/O) miniemulsion system. The zeta-potential of the copolymer particle as a function of pH indicates a sigmoid curve with an isoelectric point at pH 8.7 due to the existence of secondary amino and carboxyl groups in the copolymer chain. The obtained amphoteric particle bears positive charge under pH 8.7 and negative charge over pH 8.7. This specific property of the pH-responsive amphoteric particle is employed to separate single-stranded DNA (ssDNA). The trapped ssDNA at pH 7.0 is almost released by changing pH to 11.0, which can be carried out repeatedly.
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http://dx.doi.org/10.1002/bit.20711 | DOI Listing |
ACS Appl Mater Interfaces
January 2025
Department of Chemistry, Indian Institute of Science Education and Research Bhopal, Bhopal Bypass Road, Bhauri, Bhopal, Madhya Pradesh 462066 India.
Cellulosic nanomaterials have significantly promoted the development of sensing devices, drug delivery, and bioreactor processes. Their synthetic flexibility makes them a prominent choice for immobilizing biomolecules or cells. In this work, we developed a practical and user-friendly approach to accessing cellulose nanoparticles (CNPs).
View Article and Find Full Text PDFInt J Nanomedicine
November 2024
Department of Otorhinolaryngology, Head and Neck Surgery, Yantai Yuhuangding Hospital, Qingdao University, Yantai, People's Republic of China.
The intranasal (IN) route of drug delivery can effectively penetrate the blood-brain barrier and deliver drugs directly to the brain for the treatment of central nervous system (CNS) disorders via intra-neuronal or extra-neuronal pathways. This approach has several advantages, including avoidance of first-pass metabolism, high bioavailability, ease of administration, and improved patient compliance. In recent years, an increasing number of studies have been conducted using drugs encapsulated in solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLCs), and delivering them to the brain via the IN pathway.
View Article and Find Full Text PDFInt J Biol Macromol
November 2024
School of Fashion and Textiles, The Hong Kong Polytechnic University, Hung Hom, Kowloon 999077, Hong Kong, China. Electronic address:
J Sci Food Agric
January 2025
State Key Laboratory of Food Science and Resource, Nanchang University, Nanchang, China.
Background: Food-grade Pickering particles, particularly plant proteins, have attracted significant interest due to their bio-based nature, environmental friendliness, and edibility. Mulberry-leaf protein (MLP) is a high-quality protein with rich nutritional value and important functional properties. It has special amphoteric and emulsifying characteristics, making it valuable for use in Pickering emulsions.
View Article and Find Full Text PDFMolecules
June 2024
Faculty of Science and Engineering, Maastricht University, P.O. Box 616, 6200 MD Maastricht, The Netherlands.
Unlabelled: The thermal surface properties of graphenes and carbon materials are of crucial importance in the chemistry of materials, chemical engineering, and many industrial processes.
Background: The determination of these surface properties is carried out using inverse gas chromatography at infinite dilution, which leads to the retention volume of organic solvents adsorbed on solid surfaces. This experimental and fundamental parameter actually reflects the surface thermodynamic interactions between injected probes and solid substrates.
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