In vitro susceptibility of Mycobacterium tuberculosis clinical isolates to garenoxacin and DA-7867.

Antimicrob Agents Chemother

Servicio de Dermatología, Hospital Universitario, José E. González, Madero y Gonzalitos, Col. Mitras Centro, Monterrey, NL, México.

Published: October 2005

The in vitro activities of DA-7867, a novel oxazolidinone, and garenoxacin (BMS-284756) were compared to those of linezolid in 67 susceptible and drug-resistant clinical isolates of Mycobacterium tuberculosis. DA-7867 was the most active drug with an MIC(90) of 0.125 microg/ml, compared to the MIC(90)s of 4 microg/ml of garenoxacin and 2 microg/ml of linezolid.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1251498PMC
http://dx.doi.org/10.1128/AAC.49.10.4351-4353.2005DOI Listing

Publication Analysis

Top Keywords

mycobacterium tuberculosis
8
clinical isolates
8
vitro susceptibility
4
susceptibility mycobacterium
4
tuberculosis clinical
4
isolates garenoxacin
4
garenoxacin da-7867
4
da-7867 vitro
4
vitro activities
4
activities da-7867
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!