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International expert guidance for defining and monitoring small bowel strictures in Crohn's disease on intestinal ultrasound: a consensus statement.
Lancet Gastroenterol Hepatol
December 2024
Program for Global Translational Inflammatory Bowel Disease, Cleveland Clinic, Cleveland, OH, USA; Department of Inflammation and Immunity, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA; Department of Gastroenterology, Hepatology and Nutrition, Digestive Disease Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Background: Diagnostic imaging using CT enterography, magnetic resonance enterography, and intestinal ultrasound are important tools in evaluating stricturing Crohn's disease. Definitions of strictures have been developed for CT enterography and magnetic resonance enterography. However, expert recommendations for definitions and treatment response of strictures on intestinal ultrasound are not available.
View Article and Find Full Text PDFComparison between contrast-enhanced fat-suppressed 3D FLAIR brain MR images and T2-weighted orbital MR images at 3 Tesla for the diagnosis of acute optic neuritis.
Diagn Interv Imaging
December 2024
Department of Neuroradiology, Fondation Adolphe de Rothschild Hospital, 75019 Paris, France; Université Paris Cité, Faculté de Médecine, 75006 Paris, France.
Article Synopsis
- The study aimed to compare the effectiveness of two MRI techniques, contrast-enhanced fat-suppressed 3D FLAIR and coronal T2-weighted imaging, in diagnosing optic neuritis in patients with acute visual loss.
- A total of 1,023 patients were analyzed, and both imaging methods successfully identified optic nerve hyperintensities in 94% of those diagnosed with optic neuritis, showing good sensitivity (94%) and accuracy (89%).
- The 3D FLAIR images revealed significantly more optic disc hypersignals (30%) compared to coronal T2-weighted images (0.75%), and artifacts were more frequent in the T2-weighted images, indicating that 3D FLAIR
Peripapillary Hyperreflective Ovoid Mass-Like Structures in Stickler Syndrome.
Ophthalmol Retina
October 2024
Department of Ophthalmology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom; Department of Clinical Neurosciences, Centre for Brain Repair, University of Cambridge, Cambridge, United Kingdom; Vitreoretinal Research Group, Centre for Brain Repair, University of Cambridge, Cambridge, United Kingdom. Electronic address:
Purpose: To report a previously undescribed finding of peripapillary hyperreflective ovoid mass-like structures (PHOMS) in Stickler syndrome.
Design: Noncomparative case series.
Subjects: Twenty-two eyes with anomalous optic disc from 11 Stickler syndrome patients were identified and imaged.
A Day Saved is a Life Saved: Direct Antimicrobial Susceptibility Testing from Positively Flagged Blood Culture Bottles and their Concordance with the Routine Method.
Infect Disord Drug Targets
September 2024
Department of Microbiology, AIIMS, Jodhpur, Rajasthan, India.
Background: Sepsis is a major health problem worldwide and is associated with high morbidity and mortality with every hour delay in initiation of therapy. A conventional method of blood culture and Antimicrobial Susceptibility Testing (AST) takes around 48-72 hours. Empirical antibiotics need to be administered until the sensitivity report is made available.
View Article and Find Full Text PDFSurvival and neurological function in patients treated with extracorporeal membrane oxygenation and therapeutic hypothermia: a protocol for updating a systematic review.
BMJ Open
March 2024
Department of Nursing, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, China
Introduction: The widespread application of extracorporeal membrane oxygenation (ECMO) has enhanced clinical outcomes for patients experiencing cardiac arrest. However, its effectiveness is still limited and falls short of the desired level. Therapeutic hypothermia, which maintains body temperatures between 32°C and 36°C in cardiac arrest patients treated with ECMO, has been proposed as a potential means of neuroprotection and increased survival rates.
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