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Progress in the treatment of Alzheimer's disease based on nanosized traditional Chinese medicines.
J Mater Chem B
December 2024
West China Hospital of Sichuan University, 610041, China.
Traditional Chinese medicine (TCM) has been employed for centuries in treating and managing Alzheimer's disease (AD). However, their effective delivery to target sites can be a major challenge. This is due to their poor water solubility, low bioavailability, and potential toxicity.
View Article and Find Full Text PDFPREVALENCE OF EXHUMATION IN DISTRICT HYDERABAD: A LOCAL EXPERIENCE.
J Ayub Med Coll Abbottabad
November 2024
Bilawal Medical College LUMHS, Jamshoro-Pakistan.
Background: Exhumation of bodies for forensic purposes serves as a pivotal tool in medico-legal investigations, yet there is scant data on the practice within the Pakistani context, particularly in the District of Hyderabad. Aim & Objective were to investigate the prevalence and outcomes of exhumations in Hyderabad, contributing to the knowledge base and understanding the cultural and legal factors influencing post-mortem examinations.
Methods: A descriptive, observational, and retrospective analysis of 95 medicolegal exhumations carried out over two years, examining demographic data, the interval between death and exhumation, putrefactive changes, and the determination of the cause of death.
Enhancing postmortem diagnostics: over a decade of ISO 17020 accreditation and guidelines implementation in forensic pathology.
Forensic Sci Med Pathol
November 2024
Forensic Biomedical Sciences, Department of Imaging and Pathology, KU Leuven, Leuven, Belgium.
Forensic autopsies remain indispensable for accurately determining the cause and manner of death. However, pathologists face significant challenges inherent to the complex process of postmortem diagnostics (PMD), including the potential for diagnostic errors. The implementation of quality assurance (QA) mechanisms is crucial for minimizing these errors.
View Article and Find Full Text PDFThe Challenges of Forensic Medicine in Victim Identification in the Wake of the October 7th (2023) Mass Casualty Event.
Isr Med Assoc J
November 2024
Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center, Tel Hashomer, Israel, Reichman University, Herzliya, Israel.
Background: The massive terrorist attack on a mixed population of civilians, soldiers, and foreigners on October 7, 2023, resulted in 1200 casualties and led to many major personal identification issues. At the Israel National Center for Forensic Medicine (INCFM), addressing the mass casualty incidents required precision that included technical, ethical, and humanitarian dimensions. Many obstacles arose that were attributable to the vast number and diversity of victims and the heavy workload in the setting of a small forensic team.
View Article and Find Full Text PDFThis article brings attention to cardinal principles to consider when implementing the multidisciplinary approach with youth who are manifesting sustained coarse sexual improprieties and come to the attention of the judicial system. The obstacles of implementing therapeutic jurisprudence with this population include the persistent reliance of researchers on adult paradigms for risk assessment tools, along with treatment models that are not developmentally and gender sensitive, nor empirically supported for youth. Adherence to the scientific method is essential when constructing risk assessment tools that meet forensic standards.
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