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An Examination of the Diagnostic Utility of Ubiquitin-Specific Peptidase 6 (USP6) Rearrangement in Differentiating Nodular Fasciitis From Inflammatory Myofibroblastic Tumor: A Case Report.
Cureus
September 2024
Dermatopathology, DermLab, Birmingham, USA.
Nodular fasciitis (NF) is a benign yet diagnostically challenging mesenchymal myofibroblastic proliferation that often mimics the histological features of inflammatory myofibroblastic tumors (IMTs) and soft tissue sarcomas. The overlap in histopathological appearance, compounded by the variability in immunohistochemical (IHC) staining, frequently leads to diagnostic uncertainty. In this report, we present a case of a rapidly expanding lesion on the left medial mandible, ultimately diagnosed as NF.
View Article and Find Full Text PDFAn Inflammatory Myofibroblastic Tumour Presenting with Limited Mouth-Opening, Hypoesthaesia of The Left Chin and Infraorbital Area, Intermittent Left Eye Ptosis and Converging Strabismus.
Eur J Case Rep Intern Med
August 2024
Faculty of Medicine, University of Sousse, Susa, Tunisia.
Unlabelled: An inflammatory myofibroblastic tumour (IMT) is a rare neoplasm of mesenchymal origin, defined by myofibroblastic spindle cells accompanied by inflammatory cells, lymphocytes and eosinophils. Its symptomatology depends on the involved site and tends to mimic a malignant tumour clinically and radiologically. The head and neck region accounts for 5% of all IMTs.
View Article and Find Full Text PDFSolitary Intraosseous Myofibroma of the Mandible in a Nine-Year-Old Child: A Case Report and Literature Review.
Cureus
July 2024
Pathology, Temple University Hospital, Philadelphia, USA.
Myofibroma (MF) is a benign neoplasm derived from myofibroblasts. While they are infrequent, these tumors are predominantly found in the pediatric group and seldom manifest as intraosseous mandibular tumors. Herein, we present a 9-year-old female with a radiolucent lesion in the left mandible associated with malposed left lower canine and 1st premolar teeth.
View Article and Find Full Text PDFInflammatory myofibroblastic tumor in the mandible: A rare case report and treatment outcome.
Asian J Surg
December 2024
Department of Stomatology, Jining No.1 People's Hospital, Jining, China. Electronic address:
Clinicopathological features of myofibromas and myofibromatosis affecting the oral and maxillofacial region: A systematic review.
J Oral Pathol Med
July 2024
Oral Diagnosis Department, Piracicaba Dental School, University of Campinas, Piracicaba, Brazil.
Article Synopsis
- Myofibromas (MF) and myofibromatosis (MFT) are rare benign tumors found in the oral and maxillofacial regions, primarily affecting men and presenting as painless nodules.
- A systematic review of 169 cases revealed that MF typically appears in the gingiva for soft tissue and in the posterior mandible for intra-osseous lesions, with MFT noted for its well-circumscribed spindle cell masses.
- Surgical excision is the main treatment, and the overall prognosis is favorable, with low rates of recurrence.
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