Genetic susceptibility to human brucellosis has so far been localized to variants of genes, which participate in the specific response and the innate immune response. The Nramp1 gene, which participates in the innate response, is related to susceptibility and protection in bovine brucellosis. We examined the polymorphism of the human NRAMP1 gene in 65 patients with brucellosis and 89 healthy controls and found no significant differences in the alleles studied. Thus, variants of the NRAMP1 gene do not appear to affect susceptibility or protection in human brucellosis.
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http://dx.doi.org/10.1016/j.micinf.2005.06.010 | DOI Listing |
Microorganisms
November 2024
Key Laboratory of Ecological Safety and Sustainable Development in Arid Lands, Chinese Academy of Sciences, Lanzhou 730000, China.
The use of plant growth-promoting rhizobacteria (PGPR) for the bioremediation of heavy metal cadmium (Cd) and for enhancing plant growth in Cd-polluted soil is widely recognized as an effective approach. This study aimed to isolate Cd-resistant bacteria with plant growth-promoting (PGP) traits from the rhizosphere of vegetables subjected to metal contamination and to investigate the mechanisms associated with Cd adsorption as well as its impact on Cd uptake in lettuce. Six Cd-resistant bacterial strains were isolated from rhizosphere soil, among which the R27 strain exhibited the highest tolerance to Cd (minimum inhibitory concentration of 2000 mg/L) along with PGP traits, including phosphate solubilization (385.
View Article and Find Full Text PDFMicrobiol Res
January 2025
Key Lab of Medical Molecular Cell Biology of Shanxi Province, Institutes of Biomedical Sciences, Shanxi University, Taiyuan 030006, China. Electronic address:
Exosomal microRNAs (miRNAs) in circulation were recognized as potential biomarkers for the diagnosis of multiple diseases. However, its potential as a diagnostic hallmark for tuberculosis (TB) has yet to be explored. Here, we comprehensively analyze miRNA profiles in exosomes derived from the plasma of active TB patients and healthy persons to evaluate its efficacy in TB diagnosis.
View Article and Find Full Text PDFNat Commun
November 2024
State Key Laboratory of Plant Environmental Resilience, College of Life Sciences, Zhejiang University, Hangzhou, 310058, China.
Vet Med Sci
November 2024
Department of Animal Science, Faculty of Agriculture, University of Tabriz, Tabriz, Iran.
Plants (Basel)
September 2024
College of Agriculture, Henan University of Science and Technology, Luoyang 471023, China.
is a cadmium (Cd) and zinc (Zn) accumulator with potential for phytoextraction of soil contaminated with heavy metals. However, how Zn affects Cd accumulation in remains unclear. In this study, seedlings were treated with 100 μmol·L Zn (Zn100), 100 μmol·L Cd (Cd100), and the Zn and Cd combination (Zn100+Cd100) for 10 days under hydroponic culture.
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