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Effect of Allium sativum, Thunbergia laurifolia, and Eurycoma longifolia crude extracts on the minute intestinal fluke, Haplorchis taichui.
Trop Biomed
December 2024
Parasitic Disease Research Center, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand.
Haplorchis taichui is the minute intestinal fluke (MIF), presents a significant public health concern in Thailand. Despite praziquantel (PZQ) being the main treatment, concerns over recurrent use and drug resistance have surfaced. Thus, local herbal alternatives effective against gastrointestinal parasites could be crucial for reducing issues, necessitating exploration of herbal sources for alternative treatments.
View Article and Find Full Text PDFAnthelmintic activity and pathophysiological effect of Allium sativum crude extract against carcinogenic liver fluke, Opisthorchis viverrini.
Trop Biomed
December 2024
Parasitic Disease Research Center, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand.
Opisthorchis viverrini poses a substantial risk for cholangiocarcinoma (CCA) in Thailand. Despite praziquantel (PZQ) remains the primary treatment for opisthorchiasis, its association with adverse effects and potential CCA development during prolonged treatment, particularly in cases of reinfection and chronic infection, underscores the imperative for alternative herbal interventions with anthelmintic potential. In this context, a prior study suggested the inhibitory effects of Allium sativum L.
View Article and Find Full Text PDFLaetrile, known as vitamin B17, is often used interchangeably with amygdalin. Laetrile is a semi-synthesis product of amygdalin, whereas amygdalin is a naturally occurring substance in many plants. Both compounds have a nitrile functional group that, when activated by the intestinal enzyme β-glucosidases, releases hydrogen cyanide.
View Article and Find Full Text PDFChinese herbal formula Tongxie Yaofang granules for diarrhoea-predominant irritable bowel syndrome: a randomised, double-blind, placebo-controlled, phase II trial.
BMJ Open
January 2025
Centre for Evidence-Based Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China
Objectives: To assess the therapeutic effects and safety of Tongxie Yaofang (TXYF) granules vs placebo as an alternative treatment for diarrhoea-predominant irritable bowel syndrome (IBS-D). We hypothesised that TXYF would improve clinical responses among patients with IBS-D.
Design: A randomised, double-blind, placebo-controlled, phase II, superiority trial.
Therapeutic Efficacy of Medicinal Plants with Allopathic Medicine in Musculoskeletal Diseases.
Int J Plant Anim Environ Sci
December 2024
Department of Translational Research, College of Osteopathic Medicine of the Pacific, Western University of Health Sciences, Pomona, California, USA.
Musculoskeletal diseases encompass a diverse array of disorders affecting the muscles, bones, joints, and connective tissues, leading to significant impairments in mobility, function, and quality of life. Affecting over 1.3 billion individuals globally, musculoskeletal diseases represent a major source of disability and economic burden.
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