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Interventions supporting meaningful connections for people with serious mental illness: a concept-framed systematic narrative review.
Soc Psychiatry Psychiatr Epidemiol
January 2025
College of Education, Psychology and Social Work, Flinders University, Adelaide, Australia.
Purpose: Meaningful connections, encompassing relationships providing emotional support, understanding, acceptance, and a sense of belonging, are vital for social inclusion and well-being of Individuals with serious mental illness (SMI). The mixed methods review critically explored multifaceted approaches supporting people with SMI to foster meaningful (non-intimate) social relationships or connections.
Methods: Searches of eight electronic databases returned 4882 records.
Enhancing creative process engagement in university students: the mediating role of trust and empowerment and the moderating effect of proactive personality in humble teacher leadership.
BMC Psychol
January 2025
School of Public Administration and Policy, Dalian University of Technology, Linggong Road NO. 2, Ganjingzi District, Dalian, 116024, Liaoning, China.
This study examines the interplay between humble teacher leadership and student creative process engagement, grounded in Social Exchange Theory and Self-Determination Theory. Additionally, it analyzes the sequential mediating roles of student trust and psychological empowerment, as well as the moderating effect of proactive personality. Data were collected at three time points from 384 participants across Chinese universities and analyzed using Partial Least Squares Structural Equation Modeling (PLS-SEM) with Smart PLS 4.
View Article and Find Full Text PDFHuman epidermal growth factor receptor 2 (HER2, also known as ERBB2) signaling promotes cell growth and differentiation, and is overexpressed in several tumor types, including breast, gastric and colorectal cancer. HER2-targeted therapies have shown clinical activity against these tumor types, resulting in regulatory approvals. However, the efficacy of HER2 therapies in tumors with HER2 mutations has not been widely investigated.
View Article and Find Full Text PDFExploring health influences and the moderating role of authentic leadership in workplace bullying: A cross-sectional study among hospital nurses.
Int Nurs Rev
March 2025
Department of Foreign Languages, Fooyin University, Kaohsiung City, Taiwan.
Aim: This study explored the relationship between workplace bullying, authentic leadership, workplace friendship and nurses' health conditions and identified the predictors of nurses' health. It also explored whether authentic leadership moderated the impact of workplace bullying on their health.
Methods: This study used a cross-sectional and correlational design following the STROBE guidelines.
A constitutive interferon-high immunophenotype defines response to immunotherapy in colorectal cancer.
Cancer Cell
January 2025
Cancer Systems Biology Laboratory, The Francis Crick Institute, London NW1 1AT, UK; Centre for Cancer Evolution, Bart's Cancer Institute, Queen Mary University London, London EC1M 6AU, UK. Electronic address:
Fewer than 50% of metastatic deficient mismatch repair (dMMR) colorectal cancer (CRC) patients respond to immune checkpoint inhibition (ICI). Identifying and expanding this patient population remains a pressing clinical need. Here, we report that an interferon-high immunophenotype locally enriched in cytotoxic lymphocytes and antigen-presenting macrophages is required for response.
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