Severity: Warning
Message: file_get_contents(https://...@pubfacts.com&api_key=b8daa3ad693db53b1410957c26c9a51b4908&a=1): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
Filename: helpers/my_audit_helper.php
Line Number: 176
Backtrace:
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 176
Function: file_get_contents
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 250
Function: simplexml_load_file_from_url
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 1034
Function: getPubMedXML
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3152
Function: GetPubMedArticleOutput_2016
File: /var/www/html/application/controllers/Detail.php
Line: 575
Function: pubMedSearch_Global
File: /var/www/html/application/controllers/Detail.php
Line: 489
Function: pubMedGetRelatedKeyword
File: /var/www/html/index.php
Line: 316
Function: require_once
Objective: To establish the prevalence of the Barrett esophagus (BE) in non-selected patients who underwent upper gastrointestinal endoscopy (UGE) and identified risk factors associated.
Methods: Case-control study on patients who underwent UGE between 2001-2003. Demographic data was gathered as well as the presence of esophagitis, H. pylori, hiatal hernia presence and length, nighttime symptoms, smoking, and alcohol consumption.
Results: The global frequency of EB was 0.26%. Average age in patients with EB was 57.3 +/- 17 years old against 49 +/- 15 years old on the control group (p = 0.16). 69% of the patients with EB were men compared to 56% on the control group (p = 0.41). No difference regarding the presence of hiatal hernia was found between EB (79.6%) and patients without EB (72.5%) (p = 0.75). However, patients with EB presented a longer hiatal hernia (p < 0.05). There was no difference regarding the presence of esophagitis (p = 0.32), H. pylori (p = 0.61), smoking (p = 0.39), alcohol consumption (p = 0.34), nocturnal symptoms (p = 0.53) or extra-esophageal manifestations (p = 0.31). A significant difference existed regarding the presence of heartburn and the length of symptoms: patients with EB stated a history longer than 5 years in comparison with the control group (p < 0.005 and < 0.01 respectively).
Conclusions: The frequency of EB was 0.26% in Mexican non-selected population; the extents of hiatal hernia and history heartburn as well as a longer duration of symptoms were significantly associated to EB.
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