Populations of infertile and fertile men were screened for mutations in SPO11 and EIF5A2, two infertility candidate genes. Three heterozygous amino acid changes that might contribute to infertility were identified in the infertile group.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.fertnstert.2005.03.053 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The genetics of male infertility: a field of study whose time is now.
Arch Androl
August 2006
Department of Surgery, University of Utah, Salt Lake City, UT, USA.
Idiopathic male infertility is often associated with genetic and epigenetic abnormalities. Such abnormalities include chromosome translocations and aneuploidies, Y chromosome microdeletions, and mutations of the CFTR gene. The unraveling of the human genome and ongoing animal transgenic studies have identified numerous other genes likely to be associated with male infertility.
View Article and Find Full Text PDFScreening the SPO11 and EIF5A2 genes in a population of infertile men.
Fertil Steril
September 2005
University of Utah School of Medicine, Salt Lake City, Utah, USA.
Populations of infertile and fertile men were screened for mutations in SPO11 and EIF5A2, two infertility candidate genes. Three heterozygous amino acid changes that might contribute to infertility were identified in the infertile group.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!