Objective: To determine the response to tamoxifen in a woman with hypogonadotropic hypogonadism induced by hyperprolactinemia resistant to dopamine agonist drugs.
Design: Case report.
Setting: Academic fertility center.
Patient(s): A young woman with persistent amenorrhea, symptomatic hypogonadotropic hypogonadism, and hyperprolactinemia.
Intervention(s): Tamoxifen was administered in addition to bromocriptine.
Main Outcome Measure(s): Measurements of follicle-stimulating hormone, estradiol, prolactin, and progesterone.
Result(s): Recovery of gonadal-hypothalamic-pituitary axis.
Conclusion(s): Tamoxifen can revert the effects of chronic hypogonadotropic hypogonadism induced by hyperprolactinemia resistant to dopamine agonists.
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| http://dx.doi.org/10.1016/j.fertnstert.2005.05.006 | DOI Listing |
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