Evaluation of two TaqMan PCR assays for the detection of HIV-1 proviral DNA in blood samples.

J Microbiol Methods

Esoteric Testing, Department of Pathology, Tampa General Hospital, P.O. Box 1289, Tampa, FL 33601, USA.

Published: May 2006

This study compared two published TaqMan PCR assays targeting different regions of the HIV-1 genome for detection of HIV-1 proviral DNA. The gag specific PCR demonstrated a lower sensitivity than the assay targeting the LTR region. The LTR assay is a highly reproducible and specific technique for HIV-1 proviral DNA detection.

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http://dx.doi.org/10.1016/j.mimet.2005.08.003DOI Listing

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