Coexistence of pemphigus vulgaris and bullous pemphigoid in the upper aerodigestive tract.

Auris Nasus Larynx

Department of Otolaryngology, Doctorial Program in Comprehensive Human Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Japan.

Published: June 2006

AI Article Synopsis

  • Pemphigus vulgaris and bullous pemphigoid are rare autoimmune blistering diseases affecting the skin and mucosa, primarily caused by autoantibodies.
  • A unique case is presented involving a patient who had both conditions occurring simultaneously in the upper aerodigestive tract.
  • Diagnosis involved testing for specific autoantibodies and conducting direct immunofluorescent studies, with a review of existing literature on these coexisting conditions.

Article Abstract

Pemphigus vulgaris and bullous pemphigoid are autoimmune blistering diseases of the skin and the mucosa characterized by circulating autoantibodies. Coexistence of these lesions is extremely uncommon. We report herein a case of both pemphigus vulgaris and bullous pemphigoid which occurred in the upper aerodigestive tract. The diagnosis was made based on the circulating autoantibodies and direct immunofluorescent studies. The literature on this subject is reviewed.

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Source
http://dx.doi.org/10.1016/j.anl.2005.07.008DOI Listing

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