Novel nirK cluster genes in Nitrosomonas europaea are required for NirK-dependent tolerance to nitrite.

J Bacteriol

Evolutionary Genetics and Microbial Ecology Laboratory, School of Biological Sciences, University of Auckland, Private Bag 92019, Auckland, New Zealand.

Published: October 2005

Nitrite reductase (NirK) of Nitrosomonas europaea confers tolerance to nitrite (NO2-). The nirK gene is clustered with three genes of unknown physiological function: ncgABC. At present, this organization is unique to nitrifying bacteria. Here we report that the ncgABC gene products facilitate NirK-dependent NO2- tolerance by reversing the negative physiological effect that is associated with the activity of NirK in their absence. We hypothesize that the ncg gene products are involved in the detoxification of nitric oxide that is produced by NirK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1251594PMC
http://dx.doi.org/10.1128/JB.187.19.6849-6851.2005DOI Listing

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