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SARS-CoV-2 cross-sectional serosurvey across three HIV-1 therapeutic clinical trials in Africa.
AIDS
November 2024
Therapeutic and Vaccine Research Program, The Kirby Institute, University of New South Wales Sydney, NSW, Australia.
Objective: Data on the impact of COVID-19 in people living with HIV (PWH) are lacking in resource-constrained settings. We utilised existingrandomised clinical trials (RCTs) on antiretroviral therapies (ART) in HIV-1 infection to conduct a SARS-CoV-2 serosurvey, between January and March 2021, while characterising participants' features.
Design: Cross-sectional serosurvey.
SARS-CoV-2 seroprevalence among people living with HIV in the German HIV-1 Seroconverter Cohort, 2020-2022.
BMC Infect Dis
November 2024
Department of Infectious Diseases, Unit 18 "Sexually Transmitted Bacterial Pathogens (STI) and HIV", Robert Koch Institute, Nordufer 20, 13353, Berlin, Germany.
Objectives: People living with HIV (PLWH) are a risk group for severe symptoms and higher mortality during COVID-19. We analyzed the dynamic rise of SARS-CoV-2 seroprevalence induced by coinfections and vaccinations in PLWH in the first three years of the pandemic in Germany and compared it with corresponding data available for the general population.
Methods: Each month on average 93 blood samples from the German HIV-1 Seroconverter Cohort, a prospective longitudinal multicenter study that includes PLWH whose date of seroconversion is well defined, were received.
Seroprevalence of transfusion-transmitted infections among blood donors in Makkah, Saudi Arabia.
J Infect Dev Ctries
June 2024
Department of Clinical Laboratory Sciences, Faculty of Applied Medical Sciences, Umm Al-Qura University, Makkah, Kingdom of Saudi Arabia.
Introduction: Blood donation is vital for healthcare; however, transfusion-transmitted infections (TTIs) pose a serious risk. This study investigated the seroprevalence of TTIs among Saudi blood donors.
Methodology: This retrospective study included male blood donors aged ≥ 18 years who donated blood at Al-Noor Specialist Hospital in Makkah from January 2017 to December 2022.
Seroprevalence of immunity to hepatitis A and hepatitis B among gay, bisexual and other men who have sex with men (GBMSM) attending sexual health clinics in London and Leeds, England, 2017-2018.
Sex Transm Infect
July 2024
Blood Safety, Hepatitis, Sexually Transmitted Infections (STI) and HIV Division, UK Health Security Agency-Colindale, London, UK.
Article Synopsis
- - The study aimed to assess immunity levels for hepatitis A (HAV) and hepatitis B (HBV) among gay, bisexual, and other men who have sex with men (GBMSM) in sexual health services in England, due to limited existing data on immunization coverage.
- - Researchers analyzed residual serum samples from GBMSM attending clinics in London and Leeds, finding high immunity seroprevalence rates: 74.5% for HAV and 77.1% for HBV, with variations based on age, STI history, and clinic location.
- - The results establish a baseline for ongoing monitoring of HAV and HBV immunity in this population, highlighting that high immunity levels were observed following recent vaccination efforts and
Epidemiological and virological surveillance of the prevention of mother-to-child transmission of HIV among pregnant women in Togo.
BMC Pregnancy Childbirth
April 2024
Département de Santé Publique, Faculté des Sciences de la Santé, Université de Lomé, Lomé, Togo.
Article Synopsis
- In 2015, Togo implemented a "test-and-treat" strategy to combat mother-to-child transmission (MTCT) of HIV, yet the MTCT rate was still 3.6% in 2020, prompting a study in Lomé aimed at estimating HIV seroconversion in pregnancy and identifying at-risk pregnant women.
- The study involved a cross-sectional analysis of 3,148 umbilical cord blood samples collected from women after delivery, revealing a 3.8% seroprevalence of HIV-1, with most of the positive cases having previous knowledge of their HIV status before pregnancy.
- The findings indicated that a majority of the HIV-positive women were on antiretroviral treatment prior
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