AI Article Synopsis
- The study aimed to assess the impact of intramuscular ceftiofur on outcomes for mild clinical mastitis in lactating dairy cows, comparing it to other treatments like pirlimycin and cephapirin.
- Cows were split into different treatment groups, and initial cultures showed a predominance of gram-negative bacteria among the infections.
- Results indicated that there were no significant differences in recurrence or other outcomes related to mastitis after ceftiofur treatment, suggesting it does not improve recovery from mild clinical mastitis.
Article Abstract
The objective of this study was to evaluate the effect of intramuscular (i.m.) ceftiofur (2.2 mg/kg) on important outcomes of systemically mild clinical mastitis episodes in lactating dairy cattle. Cows with clinical mastitis were randomly assigned to a treatment group: pirlimycin intramammary (i.m.m.) (n = 35), pirlimycin i.m.m. and ceftiofur i.m.m. (n = 36), cephapirin i.m.m. (n = 40), cephapirin i.m. and ceftiofur i.m. (n = 33). Sixty-nine, 22, and 9% of initial cultures were gram-negative, gram-positive, and mixed, respectively. Logistic regression analysis showed no significant associations between treatment groups and loss of quarter, recurrence, or culling. Mixed infections, positive milk culture at 7 d after leaving hospital pen, decreased rumen motility, and absence of udder firmness were associated with increased odds of mastitis recurrence. The results suggest that i.m. ceftiofur treatment has no beneficial effects on the outcome of systemically mild clinical mastitis.
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| http://dx.doi.org/10.3168/jds.S0022-0302(05)73034-4 | DOI Listing |
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