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Exploring the impact of exercise on women with ovarian cancer: A call for more methodologically standardized RCTs to enable a realistic systematic review.
Eur J Surg Oncol
December 2024
Department of Anatomy, Faculty of Medicine and Surgery, University of Malta, Malta.
Introduction: Ovarian cancer remains a leading cause of mortality among gynecological malignancies, often diagnosed at advanced stages due to nonspecific symptoms and limited screening tools. Standard treatment, including cytoreductive surgery and chemotherapy, can cause fatigue, physical dysfunction, and psychological distress, impacting quality of life. Exercise interventions have shown potential to mitigate these effects, but inconsistent methodologies in randomized controlled trials (RCTs) limit reliable conclusions and clinical integration.
View Article and Find Full Text PDFPrescriptive Appropriateness in an Outpatient Primary and Secondary Cardiovascular Prevention Service.
High Blood Press Cardiovasc Prev
December 2024
School of Medicine and surgery, University of Milano-Bicocca, Piazza dell'ateneo nuovo 1, 20126, Milan, Italy.
Introduction: In the absence of appropriateness specific guidelines, one important cause of health resources waste could be overuse of diagnostic procedures. Since arterial hypertension is a very frequent disease there could be such a risk in its management.
Aim: To evaluate the prescriptive appropriateness of non-invasive diagnostic tests (echocardiography, carotid ultrasound, ECG exercise test, 24 h Ambulatory Blood Pressure Monitoring-ABPM) in a primary and secondary prevention outpatient's service.
Article Synopsis
- The study aimed to identify why patients with chronic heart failure (CHF) in Russia have a poor prognosis, using data from various population samples and medical records over several years.
- It established the prevalence of CHF in the Russian population, finding that 8.2% of individuals meet soft criteria for CHF, while 3.1% met strict criteria, with significant influences from conditions like hypertension and ischemic heart disease.
- The prognosis for these patients is grim, with over half dying within four years after acute decompensated heart failure (ADHF), and most patients with severe CHF not surviving beyond ten years, primarily due to inadequate medication use and poor patient follow-up.
Prescription practice and yield of chest radiography in the management of children presenting to the French pediatric emergency department with non-traumatic chest pain.
Arch Pediatr
November 2024
Department of Pediatric, University Hospital of Caen, Caen, France.
Article Synopsis
- Chest pain is common in pediatric emergencies, with most causes being benign; however, chest x-rays (CXR) are frequently ordered despite low rates of abnormalities.
- A study reviewed medical records of 599 children to assess the adherence of physicians to guidelines for CXR usage, finding that 57.1% followed the recommended algorithm and only 8.2% had abnormal CXR results.
- The findings suggest the need for improved guidelines for CXR prescriptions based on specific clinical indicators of chest pain, as current practices may overuse this test despite its limited diagnostic value.
Follow-up and transition practices in esophageal atresia: a review of European Reference Network on rare Inherited and Congenital Anomalies (ERNICA) centres and affiliates.
Pediatr Surg Int
November 2024
Stem Cell and Regenerative Medicine Section, Developmental Biology and Cancer Research, Zayed Centre for Research into Rare Disease in Children, Great Ormond Street Institute of Child Health, University College London, London, UK.
Purpose: The purpose of this study was to understand the provision and distribution of esophageal atresia (EA) follow-up (FU) and transition services across European Reference Network for rare Inherited and Congenital Anomalies (ERNICA) member and affiliate centers.
Methods: A REDCap questionnaire was sent to clinical leads of 18 ERNICA members and 14 affiliate centers.
Results: 29 of 32 centers responded (91%), the majority of which were highly specialized.
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