The objective of this study was to compare the alveolar bone growth in the 2 sides of the maxillary sinus after bilateral sinus lift procedures were performed with the simultaneous placement of dental implants in 20 consecutive patients. After elevation of the Schneiderian membrane, one side had only platelet-rich plasma (PRP) gel applied, while the other had placed only alloplastic graft material reconstituted with blood. Both open window and closed window techniques were used in ridges with > or =9 mm residual crest of bone. Results indicate that using PRP alone in cases with >7 mm residual crest can produce bone growth. Preliminary results indicate that in cases with a minimum of 7-mm crestal bone, it is possible to use a crestal approach for sinus grafting, with PRP alone and implant placement for bone growth.
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http://dx.doi.org/10.1097/01.id.0000177412.84225.05 | DOI Listing |
Sci Rep
January 2025
Department of Orthopaedics, Renmin Hospital of Wuhan University, 238 Jiefang Road, Wuhan, 430060, Hubei Province, China.
Osteosarcoma (OS) is a prevalent invasive bone cancer, with numerous homeobox family genes implicated in tumor progression. This study aimed to develop a prognostic model using HOX family genes to assess osteosarcoma patient outcomes. Data from osteosarcoma patients in The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) cohorts were collected.
View Article and Find Full Text PDFActa Ortop Mex
January 2025
Servicio de Ortopedia, Hospital de Especialidades «5 de Mayo», Instituto de Seguridad y Servicios Sociales de los Trabajadores al Servicio de los Poderes del Estado de Puebla.
Introduction: orthopedic device-associated infections (ODI) are considered surgical site infections (SSI). SSIs are generally attributed to contamination during surgery, but they require certain factors for their development. Therefore, the objective of this study was to analyze the risk factors for the development of SSIs in patients with closed fractures.
View Article and Find Full Text PDFJ Stomatol Oral Maxillofac Surg
January 2025
Center for Oral and Maxillofacial Surgery, Faculty of Medicine/Dental Medicine, Danube Private University, Krems, Austria. Electronic address:
Precise volumetric measurement of newly formed bone after maxillary sinus floor augmentation (MSFA) can help clinicians in planning for dental implants. This study aimed to introduce a novel modular framework to facilitate volumetric calculations based on manually drawn segmentations of user-defined areas of interest on cone-beam computed tomography (CBCT) images MATERIAL & METHODS: Two interconnected networks for manual segmentation of a defined volume of interest and dental implant volume calculation, respectively, were used in parallel. The volume data of dental implant manufacturers were used for reference.
View Article and Find Full Text PDFActa Biomater
January 2025
Clinical Center for Sports Medicine, Department of Orthopaedics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197 Ruijin 2nd Road, Shanghai 200025, P. R. China.. Electronic address:
Interface friction impedes tissue healing and stimulates interface cells to produce matrix metalloproteinases (MMPs); however, the precise mechanisms underlying matrix degradation, and the formation of fibrous scars remain unclear. This research involved the development of interface lubricating microspheres that inhibit the PI3K/AKT/mTOR signaling pathway in tenocytes. This inhibition significantly decreased MMP-13 expression and increased COL-1 production, thereby facilitating interface repair and regeneration.
View Article and Find Full Text PDFJ Biol Eng
January 2025
Department of Biomedical Engineering, China Medical University, Taichung, 406040, Taiwan.
Bone defects present a significant challenge in orthopedics and trauma surgery, necessitating innovative approaches to stimulate effective bone regeneration. This study investigated the potential of lithium-doped calcium silicate (LiCS) cement to enhance bone regeneration and modulate the immune microenvironment to promote tissue repair. We synthesized a LiCS ceramic powder and performed comprehensive analyses of its physicochemical properties, including phase composition, morphology, setting time, and mechanical strength.
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