A correcting formula for the estimation of harmonics-to-noise ratios (HNR) based on ensemble-averaging techniques is derived. The original method yields a biased approximation which is more accurate as the number of averaged pulses (N) increases. However, the method treats gradual waveform changes incorrectly as noise, which is worsened for large values of N. The obtained formula allows the use of as few averaged pulses as desired, while allowing the complete removal of the bias from the estimate of HNR.
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Sports Med Open
January 2025
Department of Physical Education, Tongji University, Shanghai, 200000, China.
Background: While the effects of sleep deprivation on cognitive function are well-documented, its impact on high-intensity endurance performance and underlying neural mechanisms remains underexplored, especially in the context of search and rescue operations where both physical and mental performance are essential. This study examines the neurophysiological basis of sleep deprivation on high-intensity endurance using electroencephalography (EEG). In this crossover study, twenty firefighters were subjected to both sleep deprivation (SD) and normal sleep conditions, with each participant performing endurance treadmill exercise the following morning after each condition.
View Article and Find Full Text PDFNMR Biomed
March 2025
Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
The purpose of this study was to measure T and T relaxation times of NAD proton resonances in the downfield H MRS spectrum in human brain at 7 T in vivo and to assess the propagation of relaxation time uncertainty in NAD quantification. Downfield spectra from eight healthy volunteers were acquired at multiple echo times to measure T relaxation times, and saturation recovery data were acquired to measure T relaxation times. The downfield acquisition used a spectrally selective 90° sinc pulse for excitation centered at 9.
View Article and Find Full Text PDFOpen Heart
January 2025
Department of Cardiac Surgery, University Hospital Erlangen, Erlangen, Bayern, Germany
Background: Aortic coarctation (CoA) is a congenital anomaly leading to upper-body hypertension and lower-body hypotension. Despite surgical or interventional treatment, arterial hypertension may develop and contribute to morbidity and mortality. Conventional blood pressure (BP) measurement methods lack precision for individual diagnoses and therapeutic decisions.
View Article and Find Full Text PDFJ Affect Disord
January 2025
King's Centre for Military Health Research, King's College London, SE5 9RJ, United Kingdom of Great Britain and Northern Ireland; Academic Department of Military Mental Health, King's College London, SE5 9RJ, United Kingdom of Great Britain and Northern Ireland.
Background: Heart rate variability (HRV) is governed by of sympathetic and parasympathetic regulatory systems. Post-Traumatic Stress Disorder (PTSD) may influence these systems and consequently affect cardiovascular functioning.
Methods: The sample consisted of 860 UK male military personnel approximately half of who had sustained physical combat injuries in Afghanistan.
Brain Stimul
January 2025
Department of Neurology, Duke University School of Medicine; Department of Biomedical Engineering, Duke University. Electronic address:
Objective: We aim to determine the maximum safe spatial-peak pulse-average intensity (I) of low-intensity focused ultrasound stimulation (LIFUS) in stroke patients and explore its effect on motor learning and corticospinal excitability.
Methods: We adopted the classic 3+3 design to escalate I (estimated in-vivo transcranial value) from 0, 1, 2, 4, 6, to 8 W/cm. Stopping rules were pre-defined: 2-degree scalp burn, clinical seizure, new lesion on diffusion-weighted imaging or major reduction in apparent diffusion coefficient, and participant discontinuation due to any reason.
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