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Objective: To estimate the prevalence of metabolic syndrome in Saudi male soldiers aged 20 years and above using the criteria of the National Cholesterol Education Program Adult Treatment Panel III (NCEP-ATP III).
Methods: We performed a cross-sectional survey involving a group of 2250 Saudi male soldiers aged 20-60 years residing in a military city in Northern Saudi Arabia in 2004. Participants were recruited from a primary care setting. Anthropometric data together with a brief medical history were obtained from the subjects at initial contact. Laboratory investigations were performed on the following day after fasting for 12 hours. Data on all variables required to define the metabolic syndrome according to NCEP ATP III criteria were available only for 1079 subjects who attended the laboratory for investigations (response rate: 47.9%). Data obtained from these subjects were analyzed excluding the non-respondents from the study sample.
Results: The age-adjusted prevalence of metabolic syndrome was found to be 20.8%. Abdominal obesity was the most common component in the study population (33.1%) closely followed by raised serum triglycerides (32.2%) and elevated systolic blood pressure (29.5%). Over two-thirds of the subjects (71%) exhibited at least one criterion for metabolic syndrome. Prevalence of individual factors and mean values of the components of the syndrome showed a steady increase with increase in age and body fat.
Conclusion: The estimated prevalence conforms to the rates found in other studies performed in the Middle East and elsewhere. High rates of this syndrome predict an increased burden of cardiovascular disease and diabetes among Saudis over the next few years and call for effective healthcare planning to contain this epidemic.
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Diabetol Metab Syndr
March 2025
Division of Molecular Biology, Indian Council of Medical Research - National Institute of Translational Virology and AIDS Research, 73 G MIDC Bhosari, Pune, 411026, India.
Background: This study investigates the gut microbiota components associated with metabolic syndrome in patients living with HIV-1 at Bafoussam Regional Hospital, West Cameroon, it focuses on gastrointestinal mucosal barrier disruption and dysbiosis, and their effects on persistent inflammation and metabolic disorders.
Methods: A pilot study was conducted involving fourteen patients living with HIV-1. The patients were divided into two groups of seven in each group.
AIDS Res Ther
March 2025
Department of Infectious Diseases, Tehran University of Medical Sciences, Imam Khomeini Hospital Complex, Tehran, Iran.
Concerns of increased metabolic dysfunction have been heightened for HIV patients on long-term antiretroviral therapy (ART). Among first-line ART agents, Tenofovir alafenamide (TAF) may entail a marked increase in weight compared to Tenofovir disoproxil fumarate (TDF). We retrospectively evaluated changes in weight and glucose regulation among 153 treament-naïve patients.
View Article and Find Full Text PDFBackground And Aims: The prevalence of obesity and metabolic syndrome (MetS) is rising among liver transplant (LT) candidates, many of whom have Metabolic-Associated Steatotic Liver Disease (MASLD). Following LT, untreated obesity often causes recurrent MASLD. We treated patients with obesity with LT and concurrent sleeve gastrectomy (LTSG), aiming to determine long-term impact on obesity, MetS and recurrent MASLD after transplantation.
View Article and Find Full Text PDFPhytomedicine
March 2025
Department of Rheumatology, Guang'anmen Hospital, Chinese Academy of Chinese Medical Sciences, Beijing, People's Republic of China. Electronic address:
Background: Sjögren's syndrome (SS) is a complicated autoimmune disorder, encompassing multifaceted pathogenesis of inflammatory response, immune dysregulation and metabolic abnormalities. Shaoteng Decoction (STD) is a type of traditional Chinese medicine preparation that has been shown to effectively improve inflammatory damage and immune dysfunction in patients with SS. Nevertheless, the exact mechanism has not been unspecified.
View Article and Find Full Text PDFPM R
March 2025
Department of Pain Medicine, Mayo Clinic, Jacksonville, Florida, USA.
Metabolic syndrome (MetS) is a prevalent comorbidity in patients with chronic pain conditions. Emerging evidence suggests that the relationship between MetS and chronic pain is bidirectional. This interplay involves complex mechanisms, including proinflammatory mediators in nociceptive modulation and pain-induced lifestyle changes affecting metabolic function.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!