Maltose-limited, continuous growth of the hyperthermophile Thermotoga maritima at different temperatures and dilution rates (80 degrees C/0.25 h(-1), 80 degrees C/0.17 h(-1), and 85 degrees C/0.25 h(-1)) showed that transcriptome-wide variation in gene expression within mechanical steady states was minimal compared to that between steady states, supporting the efficacy of chemostat-based approaches for functional genomics studies.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1214699PMC
http://dx.doi.org/10.1128/AEM.71.9.5572-5576.2005DOI Listing

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