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| http://dx.doi.org/10.1136/bmj.331.7516.539 | DOI Listing |
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Technology and Dementia Preconference.
Alzheimers Dement
December 2024
University of Melbourne, Parkville, VIC, Australia.
Background: Alzheimer's disease (AD) is a progressive neurodegenerative condition, with considerable variation in disease progression from the mild cognitive impairment (MCI) stage. Predicting disease progression will support prognostic decisions and patient management. Here we designed a machine learning (ML) stack model, where a classifier was used to differentiate MCI progressors from non-progressors (i.
View Article and Find Full Text PDFUntangling the Genetic Threads of Alzheimer's: Insights into Risk Factors and Biomarkers.
Curr Gene Ther
January 2025
Department of Animal Biology, Faculty of Natural Sciences, University of Tabriz, Tabriz, Iran.
Dementia is a comprehensive term that refers to illnesses characterized by a decline in cognitive memory and other cognitive functions, affecting a person's overall ability to operate. The exact causes of dementia are unknown to this day. The heterogeneity of Alzheimer's indicates the contribution of genetic polymorphism to this disease.
View Article and Find Full Text PDFThe influence of preoperative fat distribution on post-bariatric surgery body mass index and body weight loss.
Diabetes Obes Metab
January 2025
Department of General Surgery, The First Affiliated Hospital of Dalian Medical University, Dalian, People's Republic of China.
Background: The body weight following bariatric surgery is a primary concern for both healthcare professionals and surgical candidates. However, it remains unclear whether variations in preoperative fat distribution influence weight loss outcomes.
Objective: The aim of this study was to evaluate the effect of abdominal fat distribution on postoperative weight loss and body mass index (BMI) reduction, and to clarify the role of different fat depots in weight loss outcomes.
Patterns of paternity: insights into mating competition and gene flow in a recovering population of humpback whales.
R Soc Open Sci
January 2025
Sea Mammal Research Unit, Scottish Oceans Institute, School of Biology, University of St Andrews, St Andrews, Fife KY16 8LB, UK.
Variation in reproductive success is a fundamental prerequisite for sexual selection to act upon a trait. Assessing such variation is crucial in understanding a species' mating system and offers insights into population growth. Parentage analyses in cetaceans are rare, and the underlying forces of sexual selection acting on their mating behaviours remain poorly understood.
View Article and Find Full Text PDFA Systematic Review Uncovering Modifiable Influences on Statin Adherence.
Patient Prefer Adherence
January 2025
Department of Surgery & Cancer, Imperial College London, London, UK.
Statins are effective in reducing cardiovascular disease (CVD) risk, but adherence rates remain low globally. Understanding and addressing modifiable influences on adherence is key to improving outcomes. Existing reviews have methodological limitations, often failing to integrate qualitative and quantitative data or consider specific barriers to statin adherence.
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