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Genes differentially expressed in responsive and refractory acute leukemia. | LitMetric
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Genes differentially expressed in responsive and refractory acute leukemia.

Qing Wei Yao Li Li Chen Liying Zhang Xianmin He Xuping Fu Kang Ying Jianfeng Huang Qin Chen Yi Xie Yumin Mao

Front Biosci

State Key Laboratory of Genetic Engineering, Institute of Genetics, School of Life Science, Fudan University, Shanghai 200433, PR China.

Published: January 2006

DNA microarray in 22 patients with acute leukemia revealed genes which were differentially expressed. Ribosomal protein SA (RPSA), minichromosome maintenance deficient 2 (MCM2) and heterogeneous nuclear ribonucleoprotein A1 (HNRPA1) were significantly upregulated (p<0.05, t test) in refractory patients, suggesting that they may play a role in refractoriness in acute leukemia and could be biomarkers of prognosis.

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 Source
http://dx.doi.org/10.2741/1854DOI Listing

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