We present a case of fatal histoplasmosis in a patient with Addison's disease and long-term use of corticosteroid. The patient acquired Histoplasma capsulatum in China and initially presented with a laryngeal mass. He developed fulminant pneumonia and respiratory failure 9 years later. Nucleotide sequences of internal transcribed spacer regions of rRNA genes of the H. capsulatum isolate recovered from biopsied lung tissue and of the extracted fungal DNA from the laryngeal lesion were identical, indicating the recurrent nature of infection.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1234113 | PMC |
| http://dx.doi.org/10.1128/JCM.43.9.4911-4913.2005 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Introduction: Transitional-aged youth (TAY) are at a vulnerable stage of their development in which mental health and/or addiction (MHA) issues tend to manifest and/or increase in severity. These youth also tend to find themselves caught in the gap between child and adult MHA services, often resulting in sub-optimal access to and transition through MHA services. Navigation services may be one way to close this and other system gaps and improve service utilization and supports for TAY.
View Article and Find Full Text PDFSummary: An oral contraceptive pill (OCP)-induced increase in total cortisol lead to reversible suppression of the hypothalamic-pituitary-adrenal (HPA) axis and insulin resistance (IR) in a patient with Addison's disease. We suggest that this might influence the choice of an OCP in such patients. A 20-year-old female was diagnosed with Addison's disease (cortisol: 44 nmol/L, adrenocorticotropic hormone (ACTH): >500 pg/mL) and started on hydrocortisone (HC).
View Article and Find Full Text PDFNon-Contact Monitoring of Inhalation-Exhalation (I:E) Ratio in Non-Ventilated Subjects.
IEEE J Transl Eng Health Med
December 2024
Acute Care and Monitoring, Medtronic Boulder CO USA.
The inhalation-exhalation (I:E) ratio, known to be an indicator of respiratory disease, is the ratio between the inhalation phase and exhalation phase of each breath. Here, we report on results from a non-contact monitoring method for the determination of the I:E ratio. This employs a depth sensing camera system that requires no sensors to be physically attached to the patient.
View Article and Find Full Text PDFExtended-release hydrocortisone formulations - Is there a clinically meaningful benefit?
J Clin Endocrinol Metab
December 2024
Department of Clinical Medicine, University of Bergen, N-5020 BergenNorway.
Despite best practice replacement therapy with corticosteroids, patients with adrenal insufficiency report diminished quality of life and face increased mortality and morbidity. Conventional formulations of hydrocortisone have short half-lives (about 90 minutes) requiring multiple dosing during the day. Extended-release hydrocortisone (ER-HC) formulations have since 2011 been available enabling once, sometimes twice daily dosing.
View Article and Find Full Text PDFLong-term rate of heart failure in patients with autoimmune disease: A nationwide cohort study.
Eur J Heart Fail
December 2024
Department of Cardiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.
Aims: Although certain autoimmune diseases (AIDs) have been associated with an increased rate of heart failure (HF), data on the long-term rate of HF across the spectrum of AIDs are lacking. We investigated the long-term rate of HF in individuals with a history of 28 different AIDs.
Methods And Results: Individuals diagnosed with an AID (2000-2021) were identified through Danish nationwide registries.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!