Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1176/appi.ajp.162.9.1756 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Antipsychotic use during pregnancy and outcomes in pregnant individuals and newborns.
J Affect Disord
January 2025
Center for Digital Health, Medical Science Research Institute, Kyung Hee University Medical Center, Kyung Hee University College of Medicine, Seoul, South Korea; Department of Regulatory Science, Kyung Hee University, Seoul, South Korea; Department of Pediatrics, Kyung Hee University Medical Center, Kyung Hee University College of Medicine, Seoul, South Korea. Electronic address:
Background: Despite the increasing use of antipsychotics during pregnancy, comprehensive evaluations of their individual safety profiles using global data remain limited. This study aimed to assess the safety of various antipsychotics during pregnancy by comparing them to quetiapine, which has a relatively large body of safety data.
Method: Utilizing the World Health Organization pharmacovigilance database (1967-2023; n = 131,255,418 reports), we identified 11,406 reports of antipsychotic exposure during pregnancy.
Olanzapine-Induced Thrombocytopenia in a Patient With Chronic Schizophrenia: A Case Report.
Cureus
November 2024
Psychiatry, Al Amal Psychiatric Hospital, Emirates Health Services, Dubai, ARE.
Olanzapine, a second-generation antipsychotic widely used for schizophrenia, is primarily known for its efficacy in managing both positive and negative symptoms. While its metabolic side effects are well-documented, hematologic complications such as thrombocytopenia are rare and often underrecognized. A 30-year-old Middle Eastern male with a longstanding history of schizophrenia developed persistent thrombocytopenia after several years of olanzapine use, with platelet counts consistently below the normal range.
View Article and Find Full Text PDFThe Preventive Effect of Zinc Sulfate against Olanzapine-Induced Testicular Toxicity in Male Rats.
Biol Trace Elem Res
December 2024
Institute of Specific Prophylaxis and Tropical Medicine [ISPTM], Center for Pathophysiology, Infectiology and Immunology [CePII], Ocular Immunology & Infectiology, Medical University of Vienna, Vienna, Austria.
Male infertility is a complex and multifactorial clinical condition affecting a large population attributed to several factors, including perturbation in oxidative stress and the level of essential trace elements. Oxidative stress exerts multiple issues related to reproductive health, including male infertility, decreased sperm motility, sperm DNA damage, and an increased susceptibility to genetic disorders. Besides chemical toxins and food allergens in junk food items, many drugs can also lead to male infertility.
View Article and Find Full Text PDFCardiac safety of antipsychotic medications in pediatric and adolescent population: a systematic review and pathways for future research.
Eur J Pediatr
November 2024
Child and Adolescent Psychiatry Unit, Neuroscience and Human Genetics Department, Meyer Children's Hospital IRCCS 50139, Florence, Italy.
Article Synopsis
- A systematic review analyzed 10 studies involving 523 patients to evaluate how various antipsychotic medications impact the QTc interval in youngsters.
- Results indicated that risperidone and aripiprazole had minimal QTc effects, while other drugs like quetiapine and pimozide showed varying levels of prolongation, highlighting a need for more research and careful monitoring when prescribing these medications.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!