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Dyadic resilience after postpartum depression: The protective role of mother-infant respiratory sinus arrhythmia synchrony during play for maternal and child mental health across early childhood.
Dev Psychopathol
January 2025
Department of Psychological Sciences, Auburn University, Auburn, AL, USA.
Coordination in mothers' and their infants' parasympathetic nervous system functioning (i.e., respiratory sinus arrhythmia [RSA] synchrony) specifically during playful interactions may promote resilience against exposure to postpartum depressive symptoms (PPD), for both members of the dyad.
View Article and Find Full Text PDFIntranasal delivery of extracellular vesicles: A promising new approach for treating neurological and respiratory disorders.
J Control Release
January 2025
Drug Delivery Laboratory, Departamento de Ciencias y Tecnología Farmacéuticas, Universidad de Chile, Santiago, Chile; Advanced Center for Chronic Diseases (ACCDiS), Santiago, Chile; Center of New Drugs for Hypertension and Heart Failure (CENDHY), Santiago, Chile. Electronic address:
Background: Extracellular vesicles (EVs) are membrane vesicles secreted by all types of cells, including bacteria, animals, and plants. These vesicles contain proteins, nucleic acids, and lipids from their parent cells and can transfer these components between cells. EVs have attracted attention for their potential use in diagnosis and therapy due to their natural properties, such as low immunogenicity, high biocompatibility, and ability to cross the blood-brain barrier.
View Article and Find Full Text PDFPrevalence and impact of parental co-morbid anxiety and depression during the first 2 years postpartum in China.
J Affect Disord
January 2025
Department of Developmental and Behavioral Pediatrics, National Children's Medical Center, Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University, Shanghai, China; Pediatric Translational Medicine Institute, National Children's Medical Center, Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University, Shanghai, China; MOE-Shanghai Key Laboratory of Children's Environmental Health, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China; Shanghai Center for Brain Science and Brain-Inspired Technology, Shanghai, China. Electronic address:
Background: Parental postpartum co-morbid anxiety and depression negatively impact personal well-being, family dynamics, and child developmental outcomes. This study investigates the prevalence of co-morbid anxiety and depression in both mothers and fathers during the first 2 years postpartum in China, and to explore its associations with parental family support, maternal health-related quality of life (HRQoL), and child development.
Methods: This cross-sectional study was conducted in China, involving families with children aged 0-2 years who participated in community child health care.
Moderators of cognitive and behaviour therapies for prevention and treatment of anxiety disorders in children and adolescents: A systematic review and meta-analysis.
Clin Psychol Rev
January 2025
Department of Experimental Psychology, University of Oxford, Oxford, UK.
Previous studies have indicated wide variation in the effectiveness of cognitive and behaviour therapies (CBTs) for preventing and treating anxiety disorders in children and adolescents, indicating the presence of moderators influencing outcomes. This meta-analysis investigated whether sample characteristics (child age, child baseline anxiety levels, parental baseline anxiety levels) and intervention characteristics (intervention duration, facilitator contact time, facilitator background, delivery formats, parental involvement) moderate the effectiveness of CBTs for universal prevention, targeted prevention, and treatment of anxiety disorders in children and adolescents. We identified 86 eligible randomized controlled trials (RCTs) assessing the effectiveness of 98 CBTs versus non-active controls.
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