Background: Placental bed subinvolution is an underestimated cause of severe, late-onset postpartum hemorrhage.
Case: A case of placental bed subinvolution caused abnormal uterine bleeding in the late postpartum period. Because of difficulties in establishing the diagnosis, massive, intractable and life-threatening uterine hemorrhage occurred, leading to hysterectomy.
Conclusion: Early recognition of placental bed subinvolution allows the use of treatment options capable of preserving the uterus and subsequent fertility.
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Compr Physiol
December 2024
Department of Obstetrics and Gynecology, Medical University of Graz, Graz, Austria.
The proper development and function of the placenta are essential for the success of pregnancy and the well-being of both the fetus and the mother. Placental vascular function facilitates efficient fetal development during pregnancy by ensuring adequate gas exchange with low vascular resistance. This review focuses on how placental vascular function can be compromised in the pregnancy pathology preeclampsia, and conversely, how placental vascular dysfunction might contribute to this condition.
View Article and Find Full Text PDFAm J Clin Nutr
December 2024
Nantes Université, Centre Hospitalier Universitaire de Nantes INRAE, Nantes, France.
Background: Preeclampsia (PE) contributes to maternal and fetal mortality and morbidity. Supplementation with L-arginine, the precursor of nitric oxide, has not proven effective, possibly due to extensive arginine catabolism in the splanchnic bed. Citrulline is converted by the kidney to L-arginine.
View Article and Find Full Text PDFDiagnostics (Basel)
November 2024
Department of Microbiology, County Clinical Emergency Hospital, University of Medicine and Pharmacy, 200642 Craiova, Romania.
Histochem Cell Biol
November 2024
Optics and Imaging Centre, Nelson R. Mandela School of Medicine, Doris Duke Medical Research Institute, College of Health Sciences, University of KwaZulu-Natal, Durban, South Africa.
Preeclampsia, a severe pregnancy complication linked to defective placentation, poses significant maternal risks and is characterized by dysregulated angiogenic factors, including placental growth factor (PlGF) and soluble fms-like tyrosine kinase-1 (sFlt-1). Women with HIV/AIDS and receiving ART may face an increased susceptibility to preeclampsia development due to immunological and angiogenic imbalance. This study investigates the immunoexpression of these factors in the context of HIV-associated preeclampsia, utilizing morphometric image analysis.
View Article and Find Full Text PDFRev Med Inst Mex Seguro Soc
September 2024
Instituto Mexicano del Seguro Social, Hospital de Gineco Obstetricia No. 4 "Luis Castelazo Ayala", División de Obstetricia. Ciudad de México, México.
Background: Abdominal ectopic pregnancy is a rare complication with high maternal and perinatal morbimortality. The objective was to present the multidisciplinary management of an advanced abdominal ectopic pregnancy associated with COVID-19, and a review of the literature.
Clinical Case: 33-year-old multiparous patient with an abdominal ectopic pregnancy of 34 weeks, diagnosed by ultrasound at 27 weeks.
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