Objectives: To report previously unpublished data from three different types of clinical study to show the strength of the evidence purporting to demonstrate the existence of an inverse relationship between subjects' calculus and caries experience.
Methods: Data have been analysed from: a 3-year caries clinical trial of six toothpastes conducted in Lanarkshire, Scotland that involved 3000 children, Study 1; a caries epidemiological study in the Isle of Lewis that involved 228 children, Study 2; a calculus formation study carried out at Port Sunlight using a wide age range of adults, Study 3.
Results: Baseline data taken from Study 1 show that caries prevalence is highly significantly lower in calculus-prone than in calculus-free subjects (P < 0.0001). The inverse relationship is also demonstrated by the 3-year caries increment data for subjects who had used non-zinc toothpastes. Results from Study 2 show that a similar association arose for 8-year olds over a 6-year period, based on their erupting teeth alone. Finally, data from Study 3 show that whilst the extent of caries and calculus experience are both positively linked to age, within specific age groups the relationship between the two dental conditions on an individual subject basis is clearly of an inverse nature.
Conclusions: The present work confirms that calculus status has a direct bearing on both current and future caries experience. Baseline calculus status could be, and has subsequently been demonstrated to be, a useful stratifying factor for caries clinical trials.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1111/j.1600-0528.2005.00227.x | DOI Listing |
Resusc Plus
January 2025
Warwick Clinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, UK.
Aim: To assess the clinical outcomes of patients with out-of-hospital cardiac arrest attended by prehospital critical care teams compared to non-critical care teams.
Methods: This review was prospectively registered with PROSPERO and the eligibility criteria followed a PICOST framework for ILCOR systematic reviews. Prehospital critical care was defined as any provider with enhanced clinical competencies beyond standard advanced life support algorithms and dedicated dispatch to critically ill patients.
Prev Med Rep
January 2025
Division of Health Administration, College of Software and Digital Healthcare Convergence, Yonsei University, Wonju, South Korea.
Objective: With South Korea's population aging rapidly, the number of patients with type 2 diabetes mellitus (T2DM) is expected to rise, leading to worsened health outcomes and potentially straining healthcare financing. This study aimed to investigate how avoidable diabetes-related hospitalizations affect short- and long-term health expenditures.
Methods: Data from the National Health Insurance Service-Senior cohort from 2008 to 2019 in South Korea.
Comb Chem High Throughput Screen
January 2025
Department of Obstetrics and Gynecology, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.
Background: Observational studies have reported that arm fat, left leg fat, and trunk fat masses have different effects on polycystic ovarian syndrome (PCOS). However, the causal relationship between them remains unknown.
Materials And Methods: A two-sample Mendelian randomization (MR) study was conducted by utilizing pooled data from the largest Genome-Wide Association Study (GWAS).
BMC Med Educ
January 2025
Fundación Rioja Salud, Calle Piqueras 98, Logroño, 26006, Spain.
Background: In medicine, empathy refers to a predominantly cognitive attribute (rather than an emotional one), which is important as a foundation for positive physician-patient relationships. Physicians with a narcissistic personality trait have an assortment of characteristics that undermine their interpersonal functioning in clinical encounters with their patients. Evidence suggests an inverse relationship between empathy and certain characteristics of a narcissistic personality trait in general population.
View Article and Find Full Text PDFBMC Cancer
January 2025
The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi Children's Hospital, Wuxi, 214023, China.
Background: Acute myeloid leukemia (AML) is an aggressive hematological neoplasm. Little improvement in survival rates has been achieved over the past few decades. Necroptosis has relationship with certain types of malignancies outcomes.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!