Background: Peritoneal involvement is a relatively rare complication of tuberculosis, accounting for approximately 3.3% of extrapulmonary disease in the United States. Clinical diagnosis relies on a preponderance of indirect evidence and is often delayed. We describe such a patient.

Methods: An otherwise healthy 15-month-old male presented with fever, abdominal distention, vague abdominal pains, and a few episodes of watery diarrhea. Standard laboratory and radiologic work-up was unrevealing, and after a prolonged hospitalization, caseating granulomas were identified at diagnostic laparotomy.

Results: Definitive treatment was further delayed pending culture results, and the patient's condition worsened until fulminant cardiovascular collapse led to his demise.

Conclusions: Despite effective chemotherapeutic regimens, the overall mortality of tuberculous peritonitis may be as high as 51%. The diagnosis must be considered and empiric antituberculous treatment started early in the course of the disease, even if definitive diagnosis is still pending.

Download full-text PDF

Source
http://dx.doi.org/10.1089/sur.2005.6.255DOI Listing

Publication Analysis

Top Keywords

15-month-old male
8
peritoneal tuberculosis
4
tuberculosis 15-month-old
4
male surgical
4
diagnosis
4
surgical diagnosis
4
diagnosis insidious
4
insidious disease
4
disease background
4
background peritoneal
4

Similar Publications

Hepatic fibrinogen storage disease is an uncommon autosomal dominant hereditary illness marked by hypofibrinogenemia and the accumulation of variant fibrinogen in the hepatic endoplasmic reticulum. We present an asymptomatic 15-month-old male with elevated liver enzymes. Test results indicate hypofibrinogenemia.

View Article and Find Full Text PDF

Do Facial Masks Impact Infants' Joint Attention? A Within-Participant Laboratory Study.

Infancy

November 2024

Department of Psychology and Jacobs Center for Productive Youth Development, Developmental Psychology: Infancy and Childhood, University of Zurich, Zurich, Switzerland.

During the COVID-19 pandemic, children were repeatedly confronted with people wearing facial masks. Little is known, however, about how this affected young children's interactions with their caregivers. This preregistered experimental within-participants study explored whether facial masks influence young children's initiation and response to joint attention.

View Article and Find Full Text PDF
Article Synopsis
  • Poikiloderma with neutropenia (PN) is a rare genetic condition resulting from mutations in a specific gene, characterized by skin changes, ongoing low neutrophil levels, and recurrent respiratory infections.
  • A case study of a 15-month-old boy revealed symptoms like skin hyperpigmentation, growth issues, and respiratory infections, with notable physical traits such as facial dysmorphism and widespread poikiloderma.
  • Laboratory tests indicated mild neutropenia and low immunoglobulin levels, leading to treatment with immunoglobulin replacement and antibiotics, highlighting the importance of monitoring immune function in patients with recurrent infections.
View Article and Find Full Text PDF
Article Synopsis
  • The study explores the effects of Angiotensin-II and inflammation pathways on aging nephropathy, particularly their role in chronic kidney disease progression.
  • Researchers tested Losartan alone and in combination with the NF-κB inhibitor PDTC on aging rats to see if these treatments could alleviate kidney damage.
  • Results indicated that while Losartan showed some benefits, the combination of Losartan and PDTC effectively prevented kidney abnormalities, suggesting a potential new treatment strategy for age-related kidney decline.
View Article and Find Full Text PDF

Aging is characterized by oxidative stress and immune function impairment, and is associated with increased morbidity. Cannabidiol (CBD) has anti-oxidant properties, but its role in aging has been scarcely studied. This work aims to test the effect of CBD on the redox state and immunity during aging in rats.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!