Background: Although disability in activities of daily living (ADLs) is a highly dynamic process, analytic strategies for estimating active and disabled life expectancy have assumed stability in ADL function between periodic surveys spanning 12--24 months or have used interval estimation or instantaneous rates based on long assessment intervals. We performed a prospective cohort study to compare estimates of active and disabled life expectancy based on traditional assessment intervals of 1--2 years with those based on more frequent assessments at 1-month intervals.
Methods: Participants included 754 initially nondisabled community-dwelling persons, aged 70 years or older, who were interviewed monthly for 4 years to ascertain ADL disability. Estimates of active and disabled life expectancy were calculated using an increment-decrement life table for assessment intervals of 1 month, 1 year, and 2 years.
Results: For each of five age groups, the monthly assessment strategy yielded the highest values for active life expectancy and the lowest values for disabled life expectancy. The 95% confidence intervals for these values, however, overlapped the corresponding point estimates for the annual and biennial strategies.
Conclusions: Accurate estimates of active and disabled life expectancy may be obtained from epidemiologic studies that assess ADL function no more frequently than every other year.
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http://dx.doi.org/10.1093/gerona/60.8.1013 | DOI Listing |
Glob Health Res Policy
January 2025
Center for Public Health and Epidemic Preparedness and Response, Peking University, Haidian District, 38Th Xueyuan Road, Beijing, 100191, China.
Background: As population aging intensifies, it becomes increasingly important to elucidate the casual relationship between aging and changes in population health. Therefore, our study proposed to develop a systematic attribution framework to comprehensively evaluate the health impacts of population aging.
Methods: We used health-adjusted life expectancy (HALE) to measure quality of life and disability-adjusted life years (DALY) to quantify the burden of disease for the population of Guangzhou.
BMC Geriatr
January 2025
Emergency Department, Beaujon Hospital AP-HP, Clichy, France.
Background: The worldwide population is ageing and self-arm can be prevented with many techniques. Among them coercive measure consisting of physical restraint (PR) is one of the techniques. This study aims to assess the effects of the biological sex on the long-term survival after PR in geriatric patients during the initial emergency department (ED) visit.
View Article and Find Full Text PDFHist Philos Life Sci
January 2025
Faculty of Philosophy, Institute of Philosophy, Jagiellonian University, Grodzka 52, Kraków, Poland.
We revisit John Worrall's old but still prominent argument against the view that randomization balances the impact of both known and unknown confounders across the treatment and control arms. We argue that his argument involving indefinitely many possible confounders is at odds with statistical theory as it (1) presumes that the purpose of randomized studies is obtaining perfect point estimates for which perfect balance is needed; (2) mistakes equalizing each confounder with the overall (average) impact of all confounders, and (3) assumes that the joint effect of an infinite series of confounders cannot be bounded. We defend the role of randomization in balancing the impact of confounders across the treatment and control arms by putting forward the statistical sense of the balance claim.
View Article and Find Full Text PDFBMJ Open
January 2025
Pharmaceutical Sciences Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran (the Islamic Republic of).
Objectives: The main objective was to evaluate the cost-effectiveness of various medical therapy combinations in managing chronic coronary syndrome (CCS) in Iran, based on real-world and patient-level data.
Design: A cost-utility analysis employing a Markov model was conducted using data from a retrospective cohort study.
Setting: The study was conducted in the healthcare setting of Iran, focusing on primary and secondary care.
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