Hantavirus infection in Thailand: first clinical case report.

Southeast Asian J Trop Med Public Health

Department of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Published: May 2005

AI Article Synopsis

  • The study examined 115 patients with fever of unknown origin (FUO) at Siriraj Hospital between May 1999 and November 2000.
  • Five patients tested positive for IgG antibodies and eight for IgM antibodies related to Hantavirus, indicating exposure to the virus.
  • A specific case exhibited severe symptoms, suggesting that a strain of the Hantaan virus is present in Thailand and can cause illness in humans.

Article Abstract

This study involved 115 cases of fever of unknown origin (FUO) patients who were admitted to the Department of Medicine, Siriraj Hospital from May 1999 to November 2000. Among the patient sera screened by ELISA for IgG Hantavirus, five were positive for IgG Hantavirus-reacting antibodies and eight tested positive for IgM Hantavirus-reacting antibodies. One serum had both IgG and IgM antibodies. The patient exhibited acute encephalitic febrile illness, thrombocytopenia, high AST and ALT levels, and prolonged coagulation time. It appears that a form of the Hantaan virus is circulating in Thailand, which can infect humans and be pathogenic in some instances.

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Hantavirus infection in Thailand: first clinical case report.

Southeast Asian J Trop Med Public Health

May 2005

Department of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Article Synopsis
  • The study examined 115 patients with fever of unknown origin (FUO) at Siriraj Hospital between May 1999 and November 2000.
  • Five patients tested positive for IgG antibodies and eight for IgM antibodies related to Hantavirus, indicating exposure to the virus.
  • A specific case exhibited severe symptoms, suggesting that a strain of the Hantaan virus is present in Thailand and can cause illness in humans.
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Hantavirus infection in Thailand: first clinical case report.

Southeast Asian J Trop Med Public Health

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Department of Medicine at Siriraj Hospital, Mahidol University, Bangkok, Thailand.

This study involved 115 cases of Fever of Unknown Origin (FUO) in patients who were admitted to the Department of Medicine, Siriraj Hospital from May 1999 to November 2000. Among the patient sera screened by ELISA for IgG Hantavirus, five were positive for IgG Hantavirus-reacting antibodies and eight tested positive for IgM Hantavirus-reacting antibodies. One serum had both IgG and IgM antibodies.

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