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Repetitive Transcranial Magnetic Stimulation Combined with Ginkgo Diterpene Lactone Meglumine Injection Recover Cognitive and Neurological Functions of Patients with Acute Ischemic Stroke.
Actas Esp Psiquiatr
January 2025
Department of Rehabilitation Medicine, Xuzhou Central Hospital, 221000 Xuzhou, Jiangsu, China.
Background: Acute ischemic stroke (AIS) is a prevalent and challenging neurological condition associated with high mortality and morbidity rates. This study aimed to evaluate the therapeutic efficacy of repetitive transcranial magnetic stimulation (rTMS) combined with ginkgo diterpene lactone meglumine injection (GDLMI) on cognitive and neurological function recovery in patients with AIS.
Methods: A total of 120 patients with AIS, admitted between January 2021 and January 2022, received rTMS combined with GDLMI after admission.
Oxidative stress in infants of diabetic mothers: Role of ischemia modified albumin in relation to lipid peroxidation, antioxidant status and essential trace elements.
Pediatr Neonatol
December 2024
Pediatrics Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Article Synopsis
- Oxidative stress significantly impacts infants born to diabetic mothers (IDMs), leading to complications due to increased lipid peroxidation and ischemia modified albumin (IMA) levels.
- Maternal glycemic control directly influences oxidative stress markers, with higher maternal HbA1c correlating to lower total antioxidant capacity (TAC) and higher MDA and IMA levels in cord blood.
- Effective glycemic management in diabetic pregnancies is essential to mitigate oxidative stress and protect the health of infants.
Measurement of thiol/disulfide homeostasis and ischemic modified albumin levels in patients with uterine leiomyomas.
Int J Gynaecol Obstet
December 2024
Department of Gynecology and Obstetrics, University of Health Sciences Ankara City Hospital, Ankara, Turkey.
Objective: The aim is to contrast the serum levels of thiol-disulfide homeostasis and ischemic modified albumin between patients with leiomyoma and healthy individuals and to assess the impact of oxidative stress on the etiopathogenesis of leiomyoma.
Methods: In this prospective case-control study, a total of 154 participants were included, consisting of 77 cases diagnosed with leiomyoma and 77 healthy individuals without leiomyoma. The demographic characteristics and ultrasonographic findings of the participants were recorded, and parameters such as albumin, ischemia-modified albumin, and thiol-disulfide homeostasis were evaluated.
Association of serum levels of inflammation and oxidative stress markers with cognitive outcomes in multiple sclerosis; a systematic review.
J Clin Neurosci
December 2024
Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran; Research Center for Evidence-Based Medicine, Iranian EBM Center: A Joanna Briggs Institute Center of Excellence, Tabriz University of Medical Sciences, Tabriz, Iran. Electronic address:
Background: Multiple sclerosis (MS) is an immune-mediated disease with cognitive impairment being a crucial manifestation. Oxidative stress and inflammation play significant roles in the disease's pathogenesis. This systematic review explores the association between inflammation and oxidative stress markers, with cognitive outcomes in MS patients.
View Article and Find Full Text PDFThe Effect of Acute Stroke Treatment on S100B, IMA, and Thiol-Disulfide Balance.
Neurol India
November 2024
Ankara Yildirim Beyazit University, Department of Neurology, Turkey.
Article Synopsis
- The study investigates how thrombolytic therapy and endovascular thrombectomy affect certain blood markers related to brain damage in patients who had an acute ischemic stroke.
- Results showed significant changes in S100B and thiol levels in the thrombolytic therapy group, indicating a potential reduction in brain injury, whereas the levels of disulfide and ischemia-modified albumin didn't significantly change.
- The findings emphasize the need for further research to explore treatments that mitigate free radical damage during stroke recovery.
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