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Are interventional radiology techniques ideal for nonpenetrating splenic injury management: Robust statistical analysis of the Trauma Quality Program database.
PLoS One
December 2024
Department of Family Health and Preventive Medicine, Stony Brook University Renaissance School of Medicine, Stony Brook, New York, United States of America.
Background: Splenic artery embolization (SAE) is increasingly favored for adult blunt splenic injury management. We compared SAE to other splenic injury management strategies using robust statistical techniques.
Materials And Methods: Univariate analyses of demographics and outcomes were performed for four patient groups: observation, SAE, splenic surgery, splenic surgery + SAE in the American College of Surgeons Trauma Quality Program (TQIP) database.
Splenic artery embolization for trauma: a narrative review.
J Trauma Inj
December 2024
Department of Interventional Radiology, St. Luke's University Hospital, Bethlehem, PA, USA.
The management of traumatic splenic injuries has evolved significantly over the past several decades, with the majority of these injuries now being treated nonoperatively. Patients who exhibit hemodynamic instability upon initial evaluation typically require surgical intervention, while the remainder are managed conservatively. Conservative treatment for traumatic splenic injuries encompasses both medical management and splenic artery angiography, followed by embolization in cases where patients exhibit clinical signs of ongoing splenic hemorrhage.
View Article and Find Full Text PDFMitigation of sodium fluoride-induced growth inhibition, immunosuppression, hepatorenal damage, and dysregulation of oxidative stress, apoptosis, and inflammation-related genes by dietary artichoke (Cynara scolymus) leaf extract in Oreochromis niloticus.
Comp Biochem Physiol B Biochem Mol Biol
December 2024
Department of Forensic Medicine & Toxicology, College of Veterinary Medicine, University of Sadat City, Sadat city, Egypt.
This study evaluated the efficacy of integrating artichoke (Cynara scolymus) leaf extract (CSLE) into the Nile tilapia (Oreochromis niloticus) diet to mitigate fluoride (FLR) adverse effects on growth, immune components, renal and hepatic function, and the regulation of oxidative stress, inflammation, and apoptosis-related genes. A 60-day feeding experiment was conducted with 240 O. niloticus fish separated into four groups as follows: a control group (CON) fed on a basic diet, a CSLE group receiving 300 mg CSLE/kg via the diet, a FLR group exposed to 6.
View Article and Find Full Text PDFLiuweizhiji Gegen-Sangshen beverage protects against alcoholic liver disease in mice through the gut microbiota mediated SCFAs/GPR43/GLP-1 pathway.
Front Nutr
December 2024
Department of Spleen and Stomach Diseases, The Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, Sichuan, China.
Introduction: Alcoholic liver disease (ALD) is a pathological state of the liver caused by longterm alcohol consumption. Recent studies have shown that the modulation of the gut microbiota and its metabolic products, specifically the short-chain fatty acids (SCFAs), exert a critical role in the evolution and progression of ALD. The Liuweizhiji Gegen-Sangshen beverage (LGS), as a functional beverage in China, is derived from a traditional Chinese herbal formula and has been clinically applied for ALD treatment, demonstrating significant efficacy.
View Article and Find Full Text PDFPediatric blunt liver and spleen injury treated in hospitals with pediatric intensive care units: Post-hoc analysis of a multicenter, retrospective observational study.
J Pediatr Surg
December 2024
Department of Emergency and Critical Care Medicine, Keio University School of Medicine, Tokyo, Japan.
Background: We evaluated the outcomes of pediatric patients with blunt liver and spleen injury (BLSI) admitted to hospitals with pediatric intensive care units (PICUs).
Methods: A post-hoc analysis of a multicenter observational study on pediatric patients (≤16 years) with BLSI at 83 hospitals between 2008 and 2019 was conducted. Thirty-day mortality and BLSI-associated adverse events were compared between patients treated in hospitals with and without PICUs.
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