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Impact of the COVID-19 pandemic on the HIV care continuum and associated factors in middle-income countries: A mixed-methods systematic review.
HIV Med
November 2024
School of NursingP, University of British Columbia, Vancouver, British Columbia, Canada.
Introduction: The HIV care continuum during the COVID-19 era faced specific challenges. The pandemic, affecting the delivery of HIV care, exacerbated existing healthcare inequities and vulnerabilities in middle-income countries with limited financial resources. This study aims to set the stage for the systematic review, focusing on the impact of COVID-19 on HIV care in middle-income countries with a focus on barriers and facilitators.
View Article and Find Full Text PDFAcceptability and Feasibility of Using Hair Samples for Chronic Stress Measurement Among Transgender Women in Brazil.
Brain Behav
November 2024
Department of Medicine, University of California, San Francisco-UCSF, San Francisco, California, USA.
Introduction: The ability to objectively measure chronic stress has important implications for research, prevention, and treatment. Cortisol is currently the most used biological marker in the investigation of stress and can be measured via blood, saliva, and urine; however, these methods have disadvantages. The measurement of cortisol in hair is a more recently developed method that quantifies the cumulative production of cortisol over longer periods of time.
View Article and Find Full Text PDFBioengineering breakthroughs: The impact of stem cell models on advanced therapy medicinal product development.
World J Stem Cells
October 2024
Laboratory of Extracellular Matrix Biology and Cellular Interaction, Department of Anatomy, Institute of Biomedical Sciences, University of São Paulo, São Paulo 05508000, São Paulo, Brazil.
The burgeoning field of bioengineering has witnessed significant strides due to the advent of stem cell models, particularly in their application in advanced therapy medicinal products (ATMPs). In this review, we examine the multifaceted impact of these developments, emphasizing the potential of stem cell models to enhance the sophistication of ATMPs and to offer alternatives to animal testing. Stem cell-derived tissues are particularly promising because they can reshape the preclinical landscape by providing more physiologically relevant and ethically sound platforms for drug screening and disease modelling.
View Article and Find Full Text PDFHigh-performance plasmonics nanostructures in gas sensing: a comprehensive review.
Med Gas Res
March 2025
Post graduate program on material sciences, CCEN, Federal University of Pernambuco, Recife, Brazil.
Plasmonic nanostructures have emerged as indispensable components in the construction of high-performance gas sensors, playing a pivotal role across diverse applications, including industrial safety, medical diagnostics, and environmental monitoring. This review paper critically examines seminal research that underscores the remarkable efficacy of plasmonic materials in achieving superior attributes such as heightened sensitivity, selectivity, and rapid response times in gas detection. Offering a synthesis of pivotal studies, this review aims to furnish a comprehensive discourse on the contemporary advancements within the burgeoning domain of plasmonic gas sensing.
View Article and Find Full Text PDFMetabolomics: Unveiling biological matrices in precision nutrition and health.
Clin Nutr ESPEN
December 2024
IonMedicine Clinical Metabolomics, São Paulo, Brazil; Medical School of Santa Casa of São Paulo, São Paulo, Brazil.
Precision nutrition, an expanding field at the intersection of nutrition science and personalized medicine, is rapidly evolving with metabolomics integration. Metabolomics, facilitated by advanced technologies like mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectroscopy, facilitates comprehensive profiling of metabolites across diverse biological samples. From the perspective of health care systems, precision nutrition gains relevance due to the substantial impact of prevalent non-communicable diseases (NCDs) on societal well-being, which is directly linked with dietary habits and eating behavior.
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