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Cryptic presentation: primary amoebic meningoencephalitis mimicking a high-grade malignancy resulting in surgical fatality within 48 hours. Illustrative case.
J Neurosurg Case Lessons
January 2025
Neurosurgery Clinic, Birgunj, Nepal.
Background: A 71-year-old male presented with weakness of the right upper limb and headache for the past 3 months. Brain magnetic resonance imaging (MRI) with contrast showed a left frontal space-occupying lesion, suggestive of a high-grade malignancy. Awake craniotomy with complete excision of the lesion was performed under immunofluorescence guidance.
View Article and Find Full Text PDFSynthesis, Photophysical Properties and Systematic Evaluation of New Class Fluorescein Based Derivative with Organic Solvents: Spectroscopic and Density Functional Theory Methods for Optoelectronic Applications.
J Fluoresc
January 2025
Department of Physics, Jnanabharathi, Bangalore University, Bengaluru, 560056, Karnataka, India.
In this report the photophysical property of newly synthesized fluorescein based derivative 2-(5-((2,4-dichlorophenyl)diazenyl)-6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid has studied by spectroscopic and theoretical that is by Density Functional Theory technique. The structural and functional group of the synthesized molecule was confirmed by nuclear magnetic resonance and fourier transform infrared spectroscopy technique, and from the result so far obtained has been confirmed that molecule has a stable structure and confirmed the presence the functional groups present in the sample. The optical properties of the molecule are studied using the spectroscopic technique and it has revealed the solute-solvent interaction behaviour of the molecule and it has been observed that the bathochromic shift was of about 5 nm, from the fluorescence measurement it has revealed that the emission has been observed at green region and from the power spectra it has been confirmed the same.
View Article and Find Full Text PDFSelf-Diffusion of Star and Linear Polyelectrolytes in Salt-Free and Salt Solutions.
Macromolecules
January 2025
Department of Materials Science & Engineering, Texas A&M University, College Station, Texas 77840, United States.
This work explored solution properties of linear and star poly(methacrylic acids) with four, six, and eight arms (PMAA, 4PMAA, PMAA, and 8PMAA, respectively) of matched molecular weights in a wide range of pH, salt, and polymer concentrations. Experimental measurements of self-diffusion were performed by fluorescence correlation spectroscopy (FCS), and the results were interpreted using the scaling theory of polyelectrolyte solutions. While all PMAAs were pH sensitive and showed an increase in hydrodynamic radius ( ) with pH in the dilute regime, the of star polymers (measured at basic pH values) was significantly smaller for the star polyacids due to their more compact structure.
View Article and Find Full Text PDFDevelopment of a smartphone-assisted multiple colorimetric detection assay for GSH in food based on the degradation of gold nanorods.
Anal Sci
January 2025
School of Life Sciences, Shanghai University, 381 Nanchen Rd, Shanghai, 200444, China.
Glutathione (GSH) is a tripeptide and natural reducing agent composed of glutamic acid, glycine, and cysteine. Its level in the human body is closely linked to human health, such as diabetes, Alzheimer's disease, and cancer. The supplementation of exogenous GSH could bring health benefits and GSH detection in food is of considerable importance.
View Article and Find Full Text PDFOptical Imaging Guidance in Oncologic Surgery and Interventional Oncology.
Pharmacol Res
January 2025
Image-Guided Bio-Molecular Intervention Research and Division of Interventional Radiology, Department of Radiology, University of Washington School of Medicine, Seattle, USA. Electronic address:
Over recent decades, optical imaging (OI) has become an integral part of medical imaging, offering significant advantages over other modalities, such as computed tomography (CT) and magnetic resonance imaging (MRI). OI is distinguished by its real-time imaging capability, cost-effectiveness, portability, absence of ionizing radiation, and high patient acceptability. The introduction of advanced optical dyes (including FDA-approved agents like indocyanine green, Cytalux, and Gleolan) has greatly enhanced its clinical utility.
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