Objective: To compare the efficacy of fine-needle aspiration cytology (FNAC) with that of open biopsy in the evaluation of chronic epididymal lesions.
Material And Methods: Forty men evaluated for chronic epididymal lesions were studied. Men aged >25 years who did not intend to father any more children and had had local symptoms for >6 weeks were included. Of these 40 men, 23 who satisfied the above criteria were subjected to FNAC and open biopsy. The slides were reviewed by two independent pathologists. The sensitivity, specificity and positive predictive value of FNAC were compared with the results of open biopsy.
Results: Tuberculous epididymitis was the commonest cause of chronic epididymal lesions, followed by non-specific epididymitis, sperm granuloma, epdidymal cyst and normal epididymis. The sensitivity and specificity of FNAC for the diagnosis of tuberculous epididymitis were 87% and 93%, respectively. For the diagnosis of non-specific epididymitis, FNAC was 100% sensitive and 100% specific. The positive predictive value was 87% for the diagnosis of both tuberculous and non-specific epididymitis.
Conclusions: FNAC has an overall sensitivity and specificity of 90% for diagnosing chronic epididymal lesions, with a positive predictive value of 87.5%. It is a valuable tool for evaluating chronic epididymal lesions. We suggest that FNAC should be the first-choice investigation for establishing the histopathological diagnosis of epididymal lesions.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1080/00365590510031075 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Housing temperature influences exercise-induced glucose regulation and expression of exerkines in mice.
Exp Physiol
December 2024
Exercise Biological Center, China Institute of Sport Science, Beijing, China.
The impact of housing temperature on exercise-induced metabolic adaptations is not well understood, despite extensive research on the benefits of exercise for metabolic health. The aim of this study was to elucidate how housing temperatures influence the molecular responses and metabolic benefits of exercise in mice. Male C57BL/6N mice were housed at either room temperature (RT, 21°C) or in a thermoneutral environment (TN, 29°C) and subjected to either a 6-week or acute exercise regimen.
View Article and Find Full Text PDFEpididymo-Orchitis Secondary to Aeromonas hydrophila: A Rare Presentation and Case Report.
Cureus
November 2024
Department of Infection Prevention and Control, King Abdulaziz Medical City, Riyadh, SAU.
is a group of bacteria commonly found in water sources. These bacteria are known to cause gastrointestinal and skin infections, while their association with urinary tract infections is relatively rare. Here, we present a case of epididymitis in a patient with a chronic neurogenic bladder managed with clean intermittent catheterization.
View Article and Find Full Text PDFAttenuation of Chronic Oxidative Stress-Induced Testicular and Epididymal Dysfunction by Oral Intake of Lepidium meyenii in New Zealand Rabbits.
J Anim Physiol Anim Nutr (Berl)
December 2024
Department of Poultry Production, Faculty of Agriculture, Assiut University, Assiut, Egypt.
Lepidium meyenii (Maca) is a plant that has nutritional benefits and increases the effectiveness of male reproduction. In this study, oxidative stress-exposed New Zealand rabbits were used to assess the ameliorative effects of daily Maca ingestion on testicular and epididymal tissues as well as the quality of fresh and frozen/thawed sperm. Twenty-four 40-week-old, healthy New Zealand white male rabbits were divided into four groups.
View Article and Find Full Text PDFAn oral liraglutide nanomicelle formulation conferring reduced insulin-resistance and long-term hypoglycemic and lipid metabolic benefits.
J Control Release
December 2024
Department of Biomedicine, Health & Life Convergence Sciences, BK21 Four, Biomedical and Healthcare Research Institute, Mokpo National University, Jeonnam 58554, Republic of Korea; College of Pharmacy and Natural Medicine Research Institute, Mokpo National University, Jeonnam 58554, Republic of Korea. Electronic address:
Type 2 diabetes is a chronic disease characterized by insulin resistance and often worsened by obesity. Effective management involves the use of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) to assist with glycemic control and weight management. However, these drugs must be administered subcutaneously due to their low oral bioavailability.
View Article and Find Full Text PDFChronic cadmium exposure to minimal-risk doses causes dysfunction of epididymal adipose tissue and metabolic disorders.
Toxicol Appl Pharmacol
December 2024
Laboratory of Metabolomic and Chronic Degenerative Diseases, Physiology Institute, Meritorious Autonomous University of Puebla. Prol. de la 14 Sur 6301, Ciudad Universitaria, Puebla C.P. 72560, Mexico. Electronic address:
Cadmium (Cd) is among the top seven most hazardous environmental contaminants. Minimal risk levels for daily exposure have been established, such as no observable adverse effect level (NOAEL) and lowest observable adverse effect level (LOAEL). Chronic exposure to Cd, at both NOAEL and LOAEL doses, causes toxicity in diverse tissues.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!