Aims: We report on a case of combined nonarteritic anterior ischemic optic neuropathy (NAAION) and cilioretinal artery occlusion resulting from misuse of sildenafil citrate (Viagra Pfizer Pharmaceuticals, New York, NY).
Design: This is an observational case report.
Methods: A 54-year-old white man developed blindness in his left eye after an overdose of Viagra. He was examined and fully evaluated.
Results: Ocular examinations revealed a left relative afferent pupillary defect and a left combined NAAION and obstruction of the ipsilateral cilioretinal artery.
Conclusions: Although ocular side-effects of Viagra are rare, they are potentially blinding. Patients should be warned about the side-effects and against misuse of this agent.
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http://dx.doi.org/10.1089/jop.2005.21.315 | DOI Listing |
Transl Vis Sci Technol
December 2024
Departments of Neurology, Ophthalmology and Neurosurgery, CNIIC, Icahn School of Medicine at Mount Sinai, NY, USA.
Purpose: Disorders of the anterior optic nerve cause quantifiable patterns, or archetypes (AT), in visual fields (VFs) obtained using standardized automated perimetry using stimulus size III (size III). VFs with stimulus size V (size V) can reduce retest variability in eyes with moderate to severe loss. We postulated that VF testing using both stimuli would show similar ATs in eyes with glaucoma and nonarteritic anterior ischemic optic neuropathy (NAION).
View Article and Find Full Text PDFAm J Ophthalmol
December 2024
Department of Ophthalmology (O.N.K., M.S.H., L.L., Y.S., A.K.W., S.H., S.H.), Rigshospitalet, Copenhagen, Denmark; Department of Clinical Medicine (O.N.K., M.S.H., L.L., A.K.W., S.H., L.T., S.H.), University of Copenhagen, Copenhagen, Denmark.
Purpose: To determine if paracentral acute middle maculopathy (PAMM) and peripapillary intraretinal and subretinal fluid (IRF/SRF) could help distinguish between arteritic anterior ischemic optic neuropathy (A-AION) and nonarteritic AION (NA-AION) at an early stage.
Design: Nested prospective cross-sectional diagnostic accuracy study.
Methods: This study used single-center optical coherence tomography (OCT) data from 8 patients with A-AION and 24 patients with NA-AION from two prospective cross-sectional studies with consecutive sampling (ClinicalTrials.
Klin Monbl Augenheilkd
November 2024
Due to the close anatomical, functional and trophic relationships between the optic nerve and retina, a wide variety of diseases affecting both structures have reciprocal effects on each other, which must be considered in the differential diagnosis to avoid misdiagnosis. Therefore, it is essential to assess pathological changes in both structures in context to differentiate the type and location of the primary lesion from its consequences, as well as to correctly classify coincidences and disease-specific lesion patterns in both organ components.This article highlights the typical symptom constellations and lesion patterns of optic neuropathies and retinopathies.
View Article and Find Full Text PDFPurpose: The role of carotid artery disease (CAD) in the development of various types of ocular arterial occlusive disorders has often been reported. This systematic review aims to evaluate and review the current evidence regarding the role of CAD and the subsequent carotid artery hemodynamic alterations in the development of non-arteritic anterior (NA-AION) and posterior (NA-PION) ischemic optic neuropathy.
Methods: We systematically reviewed studies following Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines.
Eur J Ophthalmol
August 2024
Ophthalmic Research Center, Research Institute for Ophthalmology and Vision Science, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Introduction: This study investigated the effect of pars plana vitrectomy (VIT) versus pars plana vitrectomy combined with radial optic neurotomy (RON) on recent onset non-arteritic anterior ischemic optic neuropathy (NAION).
Methods: In this prospective interventional case series, individuals with recent-onset NAION, lower than one month and low vision (lower than 20/200) were recruited. Patients randomly underwent either VIT, or RON.
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