HLA genes in Mexican Teeneks: HLA genetic relationship with other worldwide populations.

Mol Immunol

Department of Physiology and Grupo de Estudio en Genómica y Proteómica en Enfermedades Cardiovasculares, Instituto Nacional de Cardiología Ignacio Chávez, 14080 Mexico City, Mexico.

Published: March 2006

The HLA allele frequency distribution of the Mexican Teenek Indians has been studied and compared with those of other First American Natives and worldwide populations (a total of 15694 chromosomes from 73 different populations were analyzed). This study corroborate the restricted HLA polymorphism in the Amerindian populations and demonstrate how the Amerindians show a relatively homogeneity as opposed to other First Native American groups. Finally, the present data support previous ones that state the lack of complete correlation between language and genetics in micro-environmental studies; Teenek Mayan language does not correspond with a close Mayan (Guatemala) relatedness.

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http://dx.doi.org/10.1016/j.molimm.2005.07.017DOI Listing

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