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The Stockholm early detection of cancer study (STEADY-CAN): rationale, design, data collection, and baseline characteristics for 2.7 million participants.
Eur J Epidemiol
January 2025
Department of Neurobiology, Care Sciences and Society, Division of Family Medicine and Primary Care, Karolinska Institutet, Stockholm, Sweden.
The Stockholm Early Detection of Cancer Study (STEADY-CAN) cohort was established to investigate strategies for early cancer detection in a population-based context within Stockholm County, the capital region of Sweden. Utilising real-world data to explore cancer-related healthcare patterns and outcomes, the cohort links extensive clinical and laboratory data from both inpatient and outpatient care in the region. The dataset includes demographic information, detailed diagnostic codes, laboratory results, prescribed medications, and healthcare utilisation data.
View Article and Find Full Text PDFA rare case of adult-onset vanishing white matter leukoencephalopathy with movement disorder, expressing homozygous EIF2B3 and PRKN pathogenic variants.
BMC Neurol
January 2025
Faculty of Medicine, Department of Neurology, Al-Quds University, Jerusalem, Palestine.
Background: Vanishing white matter disease (VWMD) is a rare autosomal recessive leukoencephalopathy. It is typified by a gradual loss of white matter in the brain and spinal cord, which results in impairments in vision and hearing, cerebellar ataxia, muscular weakness, stiffness, seizures, and dysarthria cogitative decline. Many reports involve minors.
View Article and Find Full Text PDFUse of a hidden Markov model for interpretation of serial cow milk paratuberculosis antibody enzyme-linked immunosorbent assay results adjusted for milk yield and quality.
Prev Vet Med
December 2024
School of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington Campus, Leicestershire LE12 5RD, United Kingdom.
Paratuberculosis (Johne's disease), caused by Mycobacterium avium subsp. paratuberculosis (MAP), is a common, economically-important and potentially zoonotic contagious disease of cattle, with worldwide distribution. Disease management relies on identification of animals which are at high-risk of being infected or infectious.
View Article and Find Full Text PDFBovine besnoitiosis: Assessment of the diagnostic accuracy of three different tests using a Bayesian latent class model approach and clinical characterization of the disease.
Prev Vet Med
December 2024
Department of Veterinary Medical Sciences, University of Bologna, Via Tolara di Sopra 50, Ozzano Emilia, BO 40064, Italy. Electronic address:
Bovine besnoitiosis, a disease caused by the tissue cyst-forming apicomplexan Besnoitia besnoiti, is re-emerging in Europe, leading to significant impairment of health and production, as well as economic losses. The early detection of the disease is of the utmost importance for the implementation of effective control measures, yet this is a challenge due to the lack of specific early clinical signs. The objectives of our study were 1) to estimate the diagnostic accuracy of three tests to detect B.
View Article and Find Full Text PDFTrue prevalence and spatial distribution of antibodies to Brucella spp. in goat populations in Hubei Province, People's Republic of China: Progress toward disease elimination.
Prev Vet Med
December 2024
National Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, China; College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China; Hubei International Scientific and Technological Cooperation Base of Veterinary Epidemiology, Huazhong Agricultural University, Wuhan, China; School of Veterinary Medicine, Murdoch University, Perth, WA, Australia. Electronic address:
Caprine brucellosis, mainly caused by Brucella melitensis, remains a significant zoonotic threat worldwide, affecting animal productivity, welfare, and public health. This study aimed to estimate the true prevalence (TP) and spatial distribution of antibodies to Brucella spp. among goat populations in Hubei Province, China.
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