Objective: The study was conducted to document the cases of adenoviral conjunctivitis, evaluate its clinical patterns, prevent its transmission and reduce its severity and complications during an epidemic.
Methods: A total of 2968 cases of adenoviral conjunctivitis were documented during the months of June, July and August 2003. By simple randomization, 200 Patients were selected and divided into two groups on the basis of treatment. Group 1 (Treatment group) 40% patients were given topical anti-histamine/decongestant eye drops whereas Group 2 (Control group) 60% patients were managed conservatively by washing eyes with cold water and applying ice packs on the eyes.
Results: Highest incidence of the disease was seen in the month of July 2003. In most of cases (90%) both eyes of the respondents were affected. Acute illness lasted from 4.91 days in Group 1 and 7.86 days in Group 2. Commonly observed symptoms included redness, watering, itching, burning, pain in the eyes and photophobia. Duration of the illness was less and severity was mild in Group 1 patients as compared with Group 2 patients this was found to be statistically significant using T test (P< 0.05). None of the cases reported any complication after complete recovery from adenoviral conjunctivitis.
Conclusion: Adenoviral conjunctivitis is a highly contagious disease and often spreads in epidemics, particularly in crowded communities with poor hygiene. Prevention of transmission is the most important therapeutic measure particularly in the ophthalmic clinics of the hospitals. Although the disease is benign and self-limiting, cold compresses and topical anti-histamine/decongestant eye drops reduce the discomfort and severity of the disease.
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Viruses
November 2024
Department of Microbiology, University of Washington School of Medicine, Seattle, WA 98109, USA.
Certain species D human adenoviruses (HAdV-D19, -D37, and -D64) are causative agents of epidemic keratoconjunctivitis. HAdV-D37 has previously been shown to bind CD46 (membrane cofactor protein) and sialic acid as adhesion receptors. HAdV-D64 is genetically highly similar to HAdV-D37, with an identical fiber protein sequence, but differs substantially in its penton base and hexon proteins, two other major capsid components, due to genetic recombination.
View Article and Find Full Text PDFTurk J Med Sci
December 2024
Department of Pediatrics Cardiology, Kayseri City Hospital, Kayseri, Turkiye.
Background/aim: Differentiating multisystem inflammatory syndrome in children (MIS-C) from adenovirus infection (AI) can be challenging due to similar clinical and laboratory findings. This study aimed to identify distinguishing characteristics and develop a scoring system to facilitate accurate diagnosis.
Materials And Methods: A comprehensive review of medical records was undertaken for 108 MIS-C patients and 259 patients with confirmed AI.
World J Virol
December 2024
Department of Ophthalmology, University Hospital of Udine, Udine 33100, Italy.
Background: Blepharoconjunctivitis poses a diagnostic challenge due to its diverse etiology, including viral infections. Blepharoconjunctivits can be acute or chronic, self-limiting, or needing medical therapy.
Aim: To review possible viral agents crucial for accurate differential diagnosis in cases of blepharoconjunctivitis.
BMJ Case Rep
December 2024
Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, Delhi, India.
BMC Ophthalmol
November 2024
Nagata Eye Clinic, 1147 Kitayamada Hohrai, Nara-City, 6310844, Nara, Japan.
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