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http://dx.doi.org/10.1210/en.2005-0689 | DOI Listing |
Mol Ecol
October 2024
Department of Life and Environmental Sciences, Marche Polytechnic University, Ancona, Italy.
Gene expression can accelerate ecological divergence by rapidly tweaking the response of an organism to novel environments, with more divergent environments exerting stronger selection and supposedly, requiring faster adaptive responses. Organisms adapted to extreme environments provide ideal systems to test this hypothesis, particularly when compared to related species with milder ecological niches. The Emperor penguin (Aptenodytes forsteri) is the only endothermic vertebrate breeding in the harsh Antarctic winter, in stark contrast with the less cold-adapted sister species, the King penguin (A.
View Article and Find Full Text PDFJMIR Res Protoc
January 2024
Department of Data Science, Prasanna School of Public Health, Manipal Academy of Higher Education, Manipal, India.
Background: Type 2 diabetes mellitus (T2DM) is one of the leading noncommunicable diseases that require diabetes self-management (DSM) practices. This study proposes to develop a customized mobile health (mHealth) app integrated with a hospital information system (HIS) to enable real-time, two-way transfer of information between the patient and physician. The captured information in the electronic health record will facilitate physicians to have a chronological account of the patient's diabetes history and enable tweaking of the treatment.
View Article and Find Full Text PDFEnviron Pollut
April 2021
Department of Microbiology, Alagappa University, Karaikudi, Tamil Nadu, India. Electronic address:
Extracellular Polymeric Substances (EPS) influenced Poly Cyclic Aromatic Hydrocarbons (PAHs) degrading Klebsiella pneumoniae was isolated from the marine environment. To increase the EPS production by Klebsiella pneumoniae, several physicochemical parameters were tweaked such as different carbon sources (arabinose, glucose, glycerol, lactose, lactic acid, mannitol, sodium acetate, starch, and sucrose at 20 g/L), nitrogen sources (ammonium chloride, ammonium sulphate, glycine, potassium nitrate, protease peptone and urea at 2 g/L), different pH, carbon/nitrogen ratio, temperature, and salt concentration were examined. Maximum EPS growth and biodegradation of Anthracene (74.
View Article and Find Full Text PDF3 Biotech
February 2021
DBT-ICT Centre for Energy Biosciences, Institute of Chemical Technology, Mumbai, India.
A marine organism, belonging to the Thraustochytrids family was isolated from mangroves of Mumbai, India. The isolated strain was identified as by internal transcribed spacer sequence analysis Optimization of process parameters yielded 14.47 g/L dry cell weight containing 55-58% oil in 3.
View Article and Find Full Text PDFMethods Mol Biol
March 2021
The Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, OH, USA.
Dendritic cells (DCs) are the bridge between innate and T cell-dependent adaptive immunity, and are promising therapeutic targets for cancer and immune-mediated disorders. In the recent past, DCs have gained significant interest to manipulate them for the treatment of cancer and immune-mediated disorders. This can be achieved by differentiating them into either immunogenic or tolerogenic DCs (TolDCs), by modulating their metabolic pathways, including glycolysis, oxidative phosphorylation, and fatty acid metabolism, to orchestrate their desired function.
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