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Article Synopsis
- A 73-year-old woman developed a quickly worsening, ulcerated growth on her eyelid that showed only slight improvement with infection treatment.
- A biopsy confirmed it was primary cutaneous anaplastic large cell lymphoma (pcALCL), a rare disorder, but no other areas of the body were affected, suggesting a good prognosis.
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Expanding the spectrum of GLI1-altered mesenchymal tumors-A high-grade uterine sarcoma harboring a novel PAMR1::GLI1 fusion and literature review of GLI1-altered mesenchymal neoplasms of the gynecologic tract.
Genes Chromosomes Cancer
February 2023
Department of Anatomical Pathology, Singapore General Hospital, Singapore, Singapore.
Article Synopsis
- GLI1-altered mesenchymal tumors include various types like pericytoma and gastroblastoma, with this report focusing on a high-grade uterine sarcoma associated with a new PAMR1::GLI1 fusion.
- A 57-year-old woman presented with a large pelvic mass, which was surgically removed and revealed aggressive tumor features, including necrosis and vascular invasion.
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Esophageal epidermoid metaplasia: an unusual condition.
Rev Esp Enferm Dig
December 2022
Aparato Digestivo, Hospital Universitario La Paz.
A 66-year-old man with a history of tobacco and alcohol consumption was diagnosed with a severe peptic esophagitis. After treatment, an endoscopy showed the resolution of esophagitis, but revealed white multinodular plaques with a diffuse distribution. Histology showed esophageal mucosa with a prominent granular layer and hyperorthokeratotis, in keeping with epidermoid metaplasia.
View Article and Find Full Text PDFCutaneous mast cell tumors in 11 miniature pigs: a retrospective study.
J Vet Diagn Invest
May 2022
Department of Population Health and Pathobiology, North Carolina State University, College of Veterinary Medicine, Raleigh, NC, USA (Rasche, Linder).
Better understanding of mast cell tumors (MCTs) in miniature pigs is needed to guide diagnosis and establish clinical significance. We characterized the gross pathology, histopathology, histochemical staining, and KIT immunoreactivity of cutaneous MCTs in a retrospective descriptive study of 11 miniature pigs (). Tumors were single or multiple papules, small nodules, or plaques.
View Article and Find Full Text PDFSuccessful treatment of recurrent advanced cutaneous squamous cell carcinoma with cemiplimab.
Dermatol Online J
October 2020
Division of Dermatology, Department of Internal Medicine, Dell Medical School at Austin, Austin, TX.
A 90-year-old man presented for evaluation of an incompletely excised squamous cell carcinoma above the right brow, with pathology demonstrating tumor extending to resection margins with perineural invasion. A cord of tumor was noted to extend past the orbital rim and towards the posterior orbit. Mohs excision versus coordinated resection and reconstruction with colleagues in the head and neck surgery and craniofacial plastic surgery departments were considered.
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