Objective: The purpose of this study was to evaluate the use of upper vaginectomy for the treatment of vaginal intraepithelial neoplasia (VAIN).
Study Design: We conducted a retrospective review. Between August 1, 1985 and April 30, 2004, 105 patients were identified who had undergone upper vaginectomy for VAIN.
Results: Thirty-six patients had previously been treated for VAIN. Mean operative time and estimated blood loss were 55 minutes and 113 mL, respectively. Ten percent had intraoperative complications. Twenty-three (22%) patients had negative findings on final pathologic examination, and invasive cancer was found in 13 (12%) patients. Four patients had postoperative complications. Follow-up was available in 52 patients; 46 (88%) remain without recurrence at a mean follow-up of 25 months.
Conclusion: In our patients, upper vaginectomy was efficacious for the treatment of VAIN. The procedure led to the diagnosis of occult invasive cancer in 12% of these women.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.ajog.2005.03.055 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Autologous Testicle Construction With Buried Metoidioplasty Correction.
Plast Reconstr Surg Glob Open
December 2024
Division of Plastic Surgery, Indiana University, Indianapolis, IN.
Gender-affirming surgery is essential for transgender individuals seeking alignment between their physical appearance and gender identity. Metoidioplasty is a masculinizing option for those assigned female at birth and often includes vaginectomy, urethral lengthening, scrotoplasty, creation of a neophallus, and testicular prostheses, typically implanted during a second-stage procedure. We describe a 39-year-old transgender man who initially underwent a laparoscopic hysterectomy, metoidioplasty, and tubularized plate urethral lengthening 19 months earlier.
View Article and Find Full Text PDFVaginal clear cell adenocarcinoma in Herlyn-Werner-Wunderlich syndrome: A case report.
World J Clin Oncol
October 2024
Department of Radiology, Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education; West China Second University Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China.
Background: Herlyn-Werner-Wunderlich (HWW) syndrome is a rare Müllerian duct anomaly, characterized by a combination of urogenital abnormalities. The occurrence of primary cervico-vaginal carcinomas in patients with HWW syndrome is exceptionally rare, posing significant challenges for screening, early diagnosis, and effective management.
Case Summary: We report a rare case of primary clear cell carcinoma of the vagina complicated in a 40-year-old woman with HWW syndrome.
Organ-sparing central pelvic compartment resection for the treatment of vulvo-vaginal melanomas.
Melanoma Manag
September 2023
Department of Gynaecological Oncology, Cambridge University Hospital, Cambridge, CB2 0QQ, UK.
Vulvo-vaginal melanomas are one of the rarest gynecological oncology diseases with a poor survival compared with other malignancies. The 5-year survival varies from 13% to 32.3%.
View Article and Find Full Text PDFSmall bowel evisceration from vagina.
J Surg Case Rep
August 2021
Colorectal Surgery, Department of Surgery, School of Clinical Science at Monash Health, Monash University, Melbourne Australia.
Vaginal evisceration is a rare condition where abdominal contents herniate through a vaginal wall defect. The estimated incidence is 0.032-1.
View Article and Find Full Text PDFSurgical techniques of phalloplasty in transgender patients: a systematic review.
Ann Transl Med
April 2021
Division of Plastic Surgery, Mayo Clinic, Jacksonville, FL, USA.
Gender confirmation surgery has a crucial role among transgender individuals. Phalloplasty is a procedure that uses flaps for phallic shaft creation. Flaps can be classified in free flaps or pedicle flaps and can be obtained from different donor sites such as forearm, thigh, abdomen, groin, and leg, and upper back.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!