AI Article Synopsis
- SIS (Small Intestinal Submucosa) is an extracellular matrix derived from pig intestine, known for its biointegration and ability to aid tissue regeneration since its discovery in 1987.
- It has shown low infection risk and has been particularly effective in urological and gynecological surgeries, including cystoplasties and repairs for urinary incontinence.
- Ongoing research aims to explore its potential applications in treating pelvic floor disorders, especially in prolapse surgery.
Article Abstract
SIS (Small Intestinal Submucosa) is an extracellular matrix isolated from pig intestine. Since its discovery in 1987, many studies have defined its structure and have demonstrated its useful biointegration and tissue regeneration properties. It also appears to be a resistant substrate associated with a low risk of infection. The role of this matrix is still under investigation in many fields of surgery, but its value has been clearly established in urological and gynaecological surgery. Several experimental and clinical studies have reported interesting results in cystoplasties, repair of stress urinary incontinence by suburethral support, urethroplasties or even chordee of the penis. Applications of this material are still to be evaluated in pelvic floor disorders, particularly in prolapse surgery.
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