AI Article Synopsis
- Pseudomonas aeruginosa is an opportunistic pathogen known for its various virulence factors, including Pseudomonas Exotoxin A (PE).
- Previously, it was established that the low-density lipoprotein receptor-related protein 1 (LRP 1) serves as the main receptor for PE.
- This study reveals that LRP 1B, a close relative of LRP 1, can also act as a receptor for Pseudomonas Exotoxin A.
Article Abstract
Pseudomonas aeruginosa is an opportunistic pathogen that produces several virulence factors, among them Pseudomonas Exotoxin A (PE). Previously, low-density lipoprotein receptor-related protein 1 (LRP 1) was shown to be the primary receptor for PE. In this report, we show that a close family member, LRP 1B, can also function as a receptor.
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| http://dx.doi.org/10.1016/j.bbadis.2005.06.007 | DOI Listing |
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