A novel one-step synthesis of 2,3-dihydro-1H-quinazolin-4-ones from 2-nitrobenzamides is reported. These reactions are mediated by stannous chloride in 0.02 M methanolic or ethanolic HCl solution and proceed in good yields.
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http://dx.doi.org/10.1021/jo050450f | DOI Listing |
Microorganisms
December 2024
Oral Care Product Development, The Procter & Gamble Company, Cincinnati, OH 45202, USA.
Various ingredients are utilized to inhibit the growth of harmful bacteria associated with cavities, gum disease, and bad breath. However, the precise mechanisms by which these ingredients affect the oral microbiome have not been fully understood at the molecular level. To elucidate the molecular mechanisms, a high-throughput bacterial transcriptomics study was conducted, and the gene expression profiles of six common oral bacteria, including two Gram-positive bacteria (, ) and four Gram-negative bacteria (, , , and ), were analyzed.
View Article and Find Full Text PDFBiosensors (Basel)
November 2024
Prokhorov General Physics Institute of the Russian Academy of Sciences, 38 Vavilov Street, 119991 Moscow, Russia.
This study presents the development of stannous chloride (SnCl)-modified glass substrates for biomolecule immobilization and their application in fabricating sensor chips for label-free interferometric biosensors. The glass modification process was optimized, identifying a 5% SnCl concentration, a 45 min reaction time, and a 150 °C drying temperature as conditions for efficient protein immobilization. Based on the SnCl-modified glass substrates and label-free spectral-phase interferometry, a biosensor was developed for the detection of aflatoxin B1 (AFB1)-a highly toxic and carcinogenic contaminant in agricultural products.
View Article and Find Full Text PDFClin Oral Investig
October 2024
Faculty of Dentistry, The University of Hong Kong, 3B12, Prince Philip Dental Hospital, 34 Hospital Road, Hong Kong SAR, 999077, China.
Objectives: To investigate the preventive and discoloring effects of a single and two weekly applications of 38% silver diamine fluoride (SDF) against dentin erosion.
Materials And Methods: 180 dentin blocks were divided into four groups. Group 1 (SDF2) received two weekly applications of 38% SDF.
Appl Radiat Isot
December 2024
Department of Neurosurgery, Jawaharlal Institute of Postgraduate Medical Education & Research, Puducherry, India.
Eur J Oral Sci
October 2024
Department of Restorative Dentistry, Institute of Science and Technology, São Paulo State University - UNESP, São José dos Campos, São Paulo, Brazil.
This study evaluated the effect of solutions containing aminomethacrylate copolymer (AA) and sodium fluoride (F; 225 ppm F) or fluoride plus stannous chloride (FSn; 225 ppm F, 800 ppm Sn) against enamel and dentin erosion/abrasion. Solutions F, FSn, AA, F+AA, FSn+AA, and deionized water as negative control were tested. Bovine enamel and dentin specimens (n = 13/solution/substrate) underwent a set of erosion-abrasion cycles (0.
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