We study the phenomenon of spatial coherence resonance in a two-dimensional model of excitable media with FitzHugh-Nagumo local dynamics. In particular, we show that there exists an optimal level of additive noise for which an inherent spatial scale of the excitable media is best pronounced. We argue that the observed phenomenon occurs due to the existence of a noise robust excursion time that is characteristic for the local dynamics whereby the diffusion constant, representing the rate of diffusive spread, determines the actual resonant spatial frequency. Additionally, biological implications of presented results in the field of neuroscience are outlined.
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http://dx.doi.org/10.1103/PhysRevE.72.016207 | DOI Listing |
J Vis Exp
December 2024
School of Life Science, Beijing University of Chinese Medicine;
Anal Methods
January 2025
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Ministry of Education), School of Pharmaceutical Sciences, Wuhan University, Wuhan, 430072, China.
In this work, a hydrophilic Eu-based ratiometric fluorescent nanosensor (PAAC-Eu) was developed for Cu ion detection in aqueous solutions and imaging in living cells. The sensor was prepared a simple one-step reaction at room temperature, leveraging the synergistic coordination of commercially accessible polyacrylic acid (PAA) and coumarin-3-carboxylic acid (CCAH) with Eu ions. PAAC-Eu was easy to disperse in aqueous media and exhibited two characteristic emission bands at 406 nm and 618 nm, respectively, upon excitation at 350 nm.
View Article and Find Full Text PDFLangmuir
January 2025
Department of Chemistry, National Institute of Technology, Rourkela, Odisha 769008, India.
Bile salts (BS) are naturally occurring steroidal biosurfactants. The ease of functionalization of BSs has boosted their use as inexpensive building blocks for the fabrication of a broad set of value-added soft functional materials. In the present work, three fluorescent bile acid (FBA) derivatives have been synthesized by conjugating anthracene at the side chain of lithocholic acid, deoxycholic acid, and cholic acid to understand the effect of the nature of the steroid nucleus on their physicochemical properties.
View Article and Find Full Text PDFJ Neurochem
January 2025
Neuroscience and Mental Health Institute, University of Alberta, Edmonton, Alberta, Canada.
The complex relationship between inflammation, its effects on neuronal excitability and the ensuing plasticity of dorsal root ganglion (DRG) sensory neurons remains to be fully explored. In this study, we have employed a system of experiments assessing the impact of inflammatory conditioned media derived from activated immune cells on the excitability and activity of DRG neurons and how this relates to subsequent growth responses of these cells. We show here that an early phase of increased neuronal activity in response to inflammatory conditioned media is critical for the engagement of plastic processes and that neuronal excitability profiles are linked through time to the structural phenotype of individual neurons.
View Article and Find Full Text PDFJ Phys Chem A
January 2025
Department of Chemistry, Lomonosov Moscow State University, Moscow 119991 Russia.
The recent detection of benzonitrile (CHCN) in the interstellar medium is one of the most fascinating discoveries in astrochemistry and molecular astrophysics. However, the mechanism of its formation in interstellar ices remains unclear. Here, we report the first evidence for the direct synthesis of benzonitrile through the radiation-induced transformations of an isolated CH···HCN complex in inert rigid media at cryogenic temperature (4.
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