AI Article Synopsis

  • Researchers used vibrating scanning polarization force microscopy to study how DNA molecules compress under radial forces.
  • By changing the vibration amplitude, they found out how much DNA compresses when forces are applied.
  • The results showed that the elastic modulus of DNA varies, being around 20-70 MPa under small forces and increasing to about 100-200 MPa when larger loads are applied.*

Article Abstract

The radial compression properties of single DNA molecules have been studied using vibrating scanning polarization force microscopy. By imaging DNA molecules at different vibration amplitude set-point values, we obtain the correlations between radially applied force and DNA compression, from which the radial compressive elasticity can be deduced. The estimated elastic modulus is approximately 20-70 MPa under small external forces (<0.4 nN) and increases to approximately 100-200 MPa for large loads.

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Source
http://dx.doi.org/10.1103/PhysRevE.71.062901DOI Listing

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