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Safety and effectiveness in an uncontrolled setting of glucagon-like-peptide-1 receptor agonists in patients with familial partial lipodystrophy: Real-life experience from a national reference network.
Diabetes Obes Metab
April 2025
Endocrinology Department, Assistance Publique-Hôpitaux de Paris (AP-HP), Saint-Antoine University Hospital, National Reference Centre for Rare Diseases of Insulin Secretion and Insulin Sensitivity (PRISIS), Paris, France.
Aim: To describe the effects of Glucagon-like peptide-1 receptor agonists (GLP-1RA) in patients with familial partial lipodystrophy (FPLD) assessed in a real-life setting in a national reference network.
Patients And Methods: We retrospectively collected clinical and metabolic parameters in patients with FPLD in the French lipodystrophy reference network, who initiated GLP-1RA. Data were recorded before, at one-year (12 ± 6 months) and at the latest follow-up on GLP-1RA therapy (≥18 months).
Improving life quality for the aged: a comprehensive post-occupancy evaluation of long-term care facilities in China.
Front Public Health
December 2024
Institute of Architectural Design and Theoretical Research, Zhejiang University, Hangzhou, China.
Article Synopsis
- - The text addresses the growing concern of improving living conditions for older adults in long-term care facilities (LTCFs) in China, highlighting the rapid development of such facilities and their often subpar physical environments that affect residents' quality of life.
- - The study evaluated 37 LTCFs through post-occupancy evaluations (POEs) using tailored assessment tools and user feedback, revealing significant deficiencies in areas like outdoor spaces, resident rooms, and staff areas, indicating unmet psychological and operational needs.
- - Ninety-two common issues were identified across eight categories, with discussions on their causes linked to various stages of facility development, aiming to inform future designs and contribute to better standards for LTCF construction.
DIABEZE: Diabetes self-management among the elderly in a Belgian home for the aged: a best practice implementation project.
JBI Evid Implement
January 2025
Zorgbedrijf Antwerpen, Hof de Beuken, Antwerp, Belgium.
Article Synopsis
- The project aimed to help elderly people in a Belgian nursing home take better care of their diabetes.
- It involved studying how things were done, checking for problems, and making improvements so everyone could work better together.
- After the changes, many health workers became more familiar with diabetes treatment, and some rules went from not being followed at all to being followed completely!*
The role of the World Guidelines for Falls Prevention and Management's risk stratification algorithm in predicting falls: a retrospective analysis of the Osteoarthritis Initiative.
Age Ageing
August 2024
Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties "G. D'Alessandro", Geriatric Unit, University Hospital Policlinic Paolo Giaccone, 90100 Palermo, Sicilia, Italy.
Article Synopsis
- Recurrent falls in older adults lead to serious health issues, prompting this study to assess the effectiveness of the World Guidelines for Falls Prevention and Management (WGFPM) risk stratification algorithm using data from the Osteoarthritis Initiative (OAI).
- The study involved 4,796 participants aged 40-80, who were categorized into low, intermediate, and high fall risk groups; the majority (82%) were identified as low risk.
- Results show that while the WGFPM algorithm had a good specificity (89.9%) for identifying those at risk of falling, its sensitivity was limited (33.7%), indicating it may miss many individuals who are actually at risk.
The effect of laughter yoga and music intervention on depression, anxiety, and stress in the Rafsanjan-Iran aged: a randomized clinical trial study.
Aging Ment Health
February 2025
Department of Community Medicine, School of Medicine, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Objectives: This study aimed to compare the effects of laughter yoga and music intervention on depression, anxiety, and stress in aged individuals referred to Rafsanjan health centers.
Method: In this 3-arm randomized clinical trial, 91 depressed aged participants aged 60-75 years, referred to Rafsanjan health centers, were randomly assigned to intervention and control groups. The study followed a parallel group design with an allocation ratio of 1:1.
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